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口腔及口咽病变:细针穿刺抽吸细胞学检查在诊断中的作用

Intraoral and Oropharyngeal Lesions: Role of Fine Needle Aspiration Cytology in the Diagnosis.

作者信息

Singhal Niti, Khurana Ujjawal, Handa Uma, Punia R P S, Mohan Harsh, Dass Arjun, Gupta Vikas

机构信息

Department of Pathology, Government Medical College & Hospital, Sector-32 B, Chandigarh, 160040 India.

Department of Otorhinolaryngology, Government Medical College & Hospital, Sector-32 B, Chandigarh, 160040 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2015 Dec;67(4):381-7. doi: 10.1007/s12070-015-0875-y. Epub 2015 Jun 30.

Abstract

The oral cavity is affected by a wide range of pathologic lesions, for which a morphologic diagnosis is required for proper management. Fine needle aspiration (FNA) is being increasingly used for preliminary diagnoses of such lesions. This is retrospective analysis of intraoral and oropharyngeal lesions diagnosed with FNAC over a period of 7 years. Out of total 55 cases, a definite diagnosis could be made on cytology in 50 cases (90.9 %). These 50 cases were further included in the study. Thirty cases were reported as non-neoplastic and 20 as neoplastic (11 benign and nine malignant). The diagnoses were made taking into account the background material (blood, mucin) and the predominant cells present (neutrophils, lymphoid cells, macrophages, hemosiderin laden macrophages, squamous cells, basaloid cells, spindle cells, giant cells). Histopathological diagnosis was available in 17 cases and corresponded with FNA diagnosis in 16 cases (94.12 %). No significant complications were seen in patients undergoing these FNAs. It can be concluded that FNA is a simple and rapid diagnostic test that can be useful for preliminary assessment of oral and oropharyngeal lesions.

摘要

口腔会受到多种病理病变的影响,对此类病变进行恰当处理需要形态学诊断。细针穿刺抽吸活检(FNA)越来越多地用于此类病变的初步诊断。这是一项对7年间经FNA诊断的口腔内和口咽病变的回顾性分析。在总共55例病例中,50例(90.9%)通过细胞学检查可做出明确诊断。这50例病例被进一步纳入研究。30例报告为非肿瘤性病变,20例为肿瘤性病变(11例良性,9例恶性)。诊断时考虑了背景物质(血液、黏液)和存在的主要细胞(中性粒细胞、淋巴细胞、巨噬细胞、含铁血黄素巨噬细胞、鳞状细胞、基底样细胞、梭形细胞、巨细胞)。17例有组织病理学诊断结果,其中16例(94.12%)与FNA诊断结果相符。接受这些FNA检查的患者未出现明显并发症。可以得出结论,FNA是一种简单快速的诊断方法,可用于口腔和口咽病变的初步评估。

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