Touska P, Oikonomou G, Ngu R, Chandra A, Malhotra A, Fry A, Oakley R, Arora A, Jeannon J-P, Simo R
Department of Radiology, Guy's and St Thomas' Hospitals NHS Foundation Trust, London, UK.
Department of ENT Surgery, Guy's and St Thomas' Hospitals NHS Foundation Trust, London, UK.
J Laryngol Otol. 2020 Sep 2:1-8. doi: 10.1017/S0022215120001929.
The global coronavirus disease 2019 (COVID-19) pandemic has necessitated rapid alterations to diagnostic pathways for head and neck cancer patients that aim to reduce risk to patients (exposure to the hospital environment) and staff (aerosol-generating procedures). Transoral fine needle aspiration cytology offers a low-risk means of rapidly diagnosing patients with oral cavity or oropharyngeal lesions. The technique was utilised in selected patients at our institution during the pandemic. The outcomes are considered in this study.
Diagnostic outcomes were retrospectively evaluated for a series of patients undergoing transoral fine needle aspiration cytology of oral cavity and oropharyngeal lesions during the COVID-19 pandemic.
Five patients underwent transoral fine needle aspiration cytology, yielding lesional material in 100 per cent, with cell blocks providing additional information. In one case, excision biopsy of a lymphoproliferative lesion was required for final diagnosis.
Transoral fine needle aspiration cytology can provide rapid diagnosis in patients with oral cavity and oropharyngeal lesions. Whilst limitations exist (including tolerability and lesion location), the technique offers significant advantages pertinent to the COVID-19 era, and could be employed in the future to obviate diagnostic surgery in selected patients.
2019年全球冠状病毒病(COVID-19)大流行使得头颈癌患者的诊断途径需要迅速改变,目的是降低对患者(暴露于医院环境)和工作人员(产生气溶胶的操作)的风险。经口细针穿刺细胞学检查提供了一种快速诊断口腔或口咽病变患者的低风险方法。在大流行期间,我们机构对选定患者采用了该技术。本研究对结果进行了评估。
对COVID-19大流行期间一系列接受口腔和口咽病变经口细针穿刺细胞学检查的患者的诊断结果进行回顾性评估。
5例患者接受了经口细针穿刺细胞学检查,100%获取了病变组织,细胞块提供了更多信息。1例患者最终诊断需要对淋巴增生性病变进行切除活检。
经口细针穿刺细胞学检查可为口腔和口咽病变患者提供快速诊断。虽然存在局限性(包括耐受性和病变位置),但该技术在COVID-19时代具有显著优势,未来可用于避免对选定患者进行诊断性手术。