Majhi Urmila, Murhekar Kanchan M, Reddy Mahendranath P, Narayanaswamy Kathiresan
Department of Pathology, Cancer Institute (WIA), Chennai, Tamil Nadu, India.
Indian J Endocrinol Metab. 2011 Jul;15(3):214-6. doi: 10.4103/2230-8210.83409.
We present here a rare case of synchronous adrenocortical carcinoma (ACC) and renal cell carcinoma (RCC). A 27-year-old woman presented with gradual abdominal distension, hematuria, and loss of weight of 3-months duration. She gave a history of treatment for hypertension. The computed axial tomography (CT) scan revealed a large retroperitoneal mass. Her urinary VMA was slightly elevated. Her 24-h urinary metanephrine level was normal. The patient underwent left adrenalectomy, left nephrectomy, spleenectomy, and distal pancreactomy with segmental colonic resection. Postoperative pathology revealed ACC of left suprarenal measuring 22 × 19 × 18 cm(3) and RCC involving the left upper pole of kidney measuring 3 × 2 × 1 cm(3).
我们在此呈现一例罕见的同步性肾上腺皮质癌（ACC）和肾细胞癌（RCC）病例。一名27岁女性，出现渐进性腹胀、血尿，病程3个月，体重减轻。她有高血压治疗史。计算机断层扫描（CT）显示腹膜后有一个大肿块。她的尿香草扁桃酸（VMA）略有升高。她的24小时尿间甲肾上腺素水平正常。患者接受了左肾上腺切除术、左肾切除术、脾切除术以及远端胰腺切除术并进行了节段性结肠切除术。术后病理显示左肾上腺ACC，大小为22×19×18 cm³，肾细胞癌累及左肾上极，大小为3×2×1 cm³。
