介孔硅负载具有聚集诱导发光特性的荧光基团用于药物递送。
Mesoporous silica functionalized with an AIE luminogen for drug delivery.
机构信息
State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun 130012, PR China.
出版信息
Chem Commun (Camb). 2011 Oct 21;47(39):11077-9. doi: 10.1039/c1cc14064g. Epub 2011 Sep 6.
PMID:21897920
Abstract
An aggregation-induced emission (AIE) luminogen, tetraphenylethene, has been successfully grafted onto mesoporous silica SBA-15 for the first time. The materials emit blue light upon UV irradiation, and are photostable for the ibuprofen (IBU) drug loading and release process, indicating their great potential for biomedical applications.
摘要
首例成功将具有聚集诱导发光（AIE）性质的四苯乙烯（TPE）接枝到介孔硅 SBA-15 上。该材料在紫外光照射下发出蓝光，且在布洛芬（IBU）药物负载和释放过程中具有良好的光稳定性，表明其在生物医学领域具有巨大的应用潜力。
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