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抗结核治疗后脉络膜结节的愈合模式:一项摄影及光学相干断层扫描研究

Healing patterns of choroidal tubercles after antitubercular therapy : A photographic and OCT study.

作者信息

Mehta Salil

机构信息

Department of Ophthalmology, Lilavati Hospital and Research Center, Bandra Reclamation, Mumbai, India,

出版信息

J Ophthalmic Inflamm Infect. 2012 Jun;2(2):95-7. doi: 10.1007/s12348-011-0040-z. Epub 2011 Sep 7.

Abstract

A 28-year-old female patient with disseminated tuberculosis and choroidal tubercles on a regimen of systemic antitubercular therapy underwent fundus photography and optical coherence tomography (OCT). This was carried out monthly until complete healing of the tubercle was seen. The tubercle consisted of a central white-yellow core, consistent with choroiditis, with a faint hyperpigmentation surrounding it. There was a surrounding diffuse rim of inflammation. By the second month, the hyperpigmented rim was more prominent as were the outer edges of both the central core and the outer rim. Over time, the outer rim had largely faded with concurrent scar formation in the core. The initial OCT analysis revealed a raised RPE-choriocapillaris complex. With healing, there was a marked reduction in the choroidal lesional height suggesting resolution.

摘要

一名28岁患有播散性肺结核且有脉络膜结核结节的女性患者,正在接受全身抗结核治疗,期间每月进行眼底照相和光学相干断层扫描(OCT),直至结核结节完全愈合。结核结节由中央白黄色核心组成,符合脉络膜炎表现,其周围有淡淡的色素沉着。周围有弥漫性炎症边缘。到第二个月,色素沉着边缘更加明显,中央核心和外缘的外边缘也是如此。随着时间推移,外缘大部分消退,同时核心处形成瘢痕。最初的OCT分析显示视网膜色素上皮-脉络膜毛细血管复合体隆起。随着愈合,脉络膜病变高度明显降低,提示病变消退。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6e4/3345054/42ac5b689cd5/12348_2011_40_Fig1_HTML.jpg

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