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自发性脾破裂作为肺恶性肿瘤的首发表现导致急腹症:一例病例报告

Acute abdomen due to spontaneous splenic rupture as the first presentation of lung malignancy: a case report.

作者信息

Kyriacou Angelos, Arulraj Nolan, Varia Haren

机构信息

Department of Medicine, Whinney Heys Road, Blackpool Victoria Hospital, Blackpool, FY3 8NR, UK.

出版信息

J Med Case Rep. 2011 Sep 7;5:444. doi: 10.1186/1752-1947-5-444.

Abstract

INTRODUCTION

Spontaneous splenic rupture is well recognized in the context of hematological malignancies (lymphoproliferative and myeloproliferative disorders); a few case reports have also linked solid tumors, such as pancreatic and liver cancer, with the occurrence of spontaneous splenic rupture. This is the first case report of lung cancer as a likely cause of spontaneous splenic rupture.

CASE PRESENTATION

A 61-year-old Caucasian woman presented to our hospital with non-specific symptoms. She developed an 'acute' abdomen and went into a state of shock within twelve hours of her presentation. She was diagnosed with spontaneous splenic rupture with radiology and following a laparotomy. She made an uneventful recovery postoperatively and was simultaneously found to have a bronchial adenocarcinoma.

CONCLUSION

Spontaneous splenic rupture is a potentially fatal but often unrecognized cause of acute abdomen. It should be routinely considered in the differential diagnosis of acute ('surgical') abdomen and when present it should be promptly dealt with, most commonly with a laparotomy. Once the diagnosis is confirmed there should be an aggressive drive to identify an underlying etiology; malignancy is the commonest culprit. Solid tumors should be considered as underlying causes despite being less common than hematological neoplasms. This case report demonstrates lung malignancy as an underlying precipitating cause of spontaneous splenic rupture.

摘要

引言

自发性脾破裂在血液系统恶性肿瘤(淋巴增殖性和骨髓增殖性疾病)的背景下已得到充分认识;也有一些病例报告将实体瘤,如胰腺癌和肝癌,与自发性脾破裂的发生联系起来。这是首例将肺癌作为自发性脾破裂可能病因的病例报告。

病例介绍

一名61岁的白人女性因非特异性症状前来我院就诊。她出现了“急腹症”,并在就诊后12小时内陷入休克状态。经放射学检查及剖腹手术后,她被诊断为自发性脾破裂。她术后恢复顺利,同时被发现患有支气管腺癌。

结论

自发性脾破裂是急腹症的一个潜在致命但常未被认识的病因。在急性(“外科性”)腹痛的鉴别诊断中应常规考虑该病,一旦出现应及时处理,最常见的处理方式是剖腹手术。一旦确诊,应积极寻找潜在病因;恶性肿瘤是最常见的罪魁祸首。实体瘤虽不如血液系统肿瘤常见,但也应被视为潜在病因。本病例报告显示肺部恶性肿瘤是自发性脾破裂的潜在促发原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a934/3178521/d2177787e0e9/1752-1947-5-444-1.jpg

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