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The social aspects of EMT-MET plasticity.

作者信息

Thompson E W, Haviv I

出版信息

Nat Med. 2011 Sep 7;17(9):1048-9. doi: 10.1038/nm.2437.

DOI:10.1038/nm.2437
PMID:21900919
Abstract
摘要

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Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization.miR-200s 通过直接靶向 Sec23a 影响癌细胞分泌组并促进转移定植。
Nat Med. 2011 Aug 7;17(9):1101-8. doi: 10.1038/nm.2401.
2
Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast.旁分泌和自分泌信号诱导和维持乳腺中的间充质和干细胞状态。
Cell. 2011 Jun 10;145(6):926-40. doi: 10.1016/j.cell.2011.04.029.
3
Hallmarks of cancer: the next generation.癌症的特征：下一代。
肝细胞癌中的液体活检：循环肿瘤DNA作为诊断和预后的潜在生物标志物
Curr Oncol Rep. 2025 May 9. doi: 10.1007/s11912-025-01681-3.
4
Exploring the role of EMT in ovarian cancer progression using a multiscale mathematical model.使用多尺度数学模型探索上皮-间质转化在卵巢癌进展中的作用。
NPJ Syst Biol Appl. 2025 Apr 17;11(1):36. doi: 10.1038/s41540-025-00508-y.
5
Point-of-care testing for early-stage liver cancer diagnosis and personalized medicine: Biomarkers, current technologies and perspectives.用于早期肝癌诊断和个性化医疗的即时检测：生物标志物、现有技术及展望
Heliyon. 2024 Sep 25;10(19):e38444. doi: 10.1016/j.heliyon.2024.e38444. eCollection 2024 Oct 15.
6
Epithelial-mesenchymal plasticity in cancer: signaling pathways and therapeutic targets.癌症中的上皮-间质可塑性：信号通路与治疗靶点。
MedComm (2020). 2024 Aug 1;5(8):e659. doi: 10.1002/mco2.659. eCollection 2024 Aug.
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Distinctive Expression of MetastamiRs in Breast Cancer Mesenchymal Stem Cells Isolated from Solid Tumor.乳腺癌实体瘤来源的间充质干细胞中转移性微小 RNA 的特征性表达。
Curr Stem Cell Res Ther. 2024;19(11):1525-1534. doi: 10.2174/011574888X272313231124063458.
8
Heterogeneity and plasticity of epithelial-mesenchymal transition (EMT) in cancer metastasis: Focusing on partial EMT and regulatory mechanisms.肿瘤转移中上皮-间质转化（EMT）的异质性和可塑性：关注部分 EMT 和调控机制。
Cell Prolif. 2023 Jun;56(6):e13423. doi: 10.1111/cpr.13423. Epub 2023 Feb 19.
9
Clinical Applications of Liquid Biopsy in Hepatocellular Carcinoma.液体活检在肝细胞癌中的临床应用
Front Oncol. 2022 Feb 8;12:781820. doi: 10.3389/fonc.2022.781820. eCollection 2022.
10
Role of the epithelial-mesenchymal transition-related circular RNA, circ-10720, in non-small-cell lung cancer.上皮-间质转化相关环状RNA circ-10720在非小细胞肺癌中的作用
Transl Lung Cancer Res. 2021 Apr;10(4):1804-1818. doi: 10.21037/tlcr-20-920.
Cell. 2011 Mar 4;144(5):646-74. doi: 10.1016/j.cell.2011.02.013.
4
An ESRP-regulated splicing programme is abrogated during the epithelial-mesenchymal transition.ESRP 调控的剪接程序在上皮-间充质转化过程中被废除。
EMBO J. 2010 Oct 6;29(19):3286-300. doi: 10.1038/emboj.2010.195. Epub 2010 Aug 13.
5
Breast carcinoma cells re-express E-cadherin during mesenchymal to epithelial reverting transition.乳腺癌细胞在间质到上皮逆转转化过程中重新表达 E-钙黏蛋白。
Mol Cancer. 2010 Jul 7;9:179. doi: 10.1186/1476-4598-9-179.
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Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer.人乳腺癌细胞系中的上皮间质转化特征与人乳腺癌中 CD44(hi/)CD24(lo/-) 干细胞表型平行。
J Mammary Gland Biol Neoplasia. 2010 Jun;15(2):235-52. doi: 10.1007/s10911-010-9175-z. Epub 2010 Jun 4.
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Nat Cell Biol. 2008 May;10(5):593-601. doi: 10.1038/ncb1722. Epub 2008 Mar 30.
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Co-culturing human prostate carcinoma cells with hepatocytes leads to increased expression of E-cadherin.将人前列腺癌细胞与肝细胞共培养会导致E-钙黏蛋白表达增加。
Br J Cancer. 2007 Apr 23;96(8):1246-52. doi: 10.1038/sj.bjc.6603700. Epub 2007 Apr 3.