Adauwiyah J, Suraiya H H
Pusat Perubatan Universiti Kebangsaan Malaysia, Kuala Lumpur.
Med J Malaysia. 2010 Dec;65(4):297-9.
Psoralen and ultraviolet light A (PUVA) was the mainstay of vitiligo treatment before the introduction of narrowband UVB(NB-UVB). Eighteen patients treated with NB-UVB in Hospital Kuala Lumpur were retrospectively analyzed. Eight patients had Fitzpatrick skin phototype III and 10 with phototype IV. The mean duration of disease was 7.3 +/- 5.4 years, and the mean body surface area affected was 19.3 +/- 16.2%. Mean duration of treatment was 14.3 +/- 9.6 months, number of session 113.5 +/- 88.6 times and cumulative dose 111.7 +/- 108.5 J/ cm2. Concomitant topical steroid was used in 88.9% patients. Repigmentation was moderate in 6 (40%) patients, good in 3 (20%), while 3 (20%) achieved excellent results. One patient (6.6%) showed no response and 2 (13.3%) showed poor repigmentation. Three patients developed side effects. NB-UVB phototherapy results in satisfactory repigmentation in our vitiligo patients and should be offered as a treatment option.
在窄谱中波紫外线（NB - UVB）出现之前，补骨脂素加紫外线A（PUVA）是白癜风治疗的主要方法。对吉隆坡医院18例接受NB - UVB治疗的患者进行回顾性分析。8例患者为Fitzpatrick皮肤光类型III型，10例为IV型。疾病的平均病程为7.3±5.4年，平均受累体表面积为19.3±16.2%。平均治疗时间为14.3±9.6个月，治疗次数为113.5±88.6次，累积剂量为111.7±108.5 J/cm²。88.9%的患者同时使用了外用类固醇。6例（40%）患者色素沉着为中度，3例（20%）为良好，3例（20%）取得了优异效果。1例患者（6.6%）无反应，2例（13.3%）色素沉着不佳。3例患者出现了副作用。NB - UVB光疗在我们的白癜风患者中导致了令人满意的色素沉着，应作为一种治疗选择提供。
