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教学社区医院的机器人根治性前列腺切除术:结果与安全性

Robotic radical prostatectomy at a teaching community hospital: outcomes and safety.

作者信息

Padavano Julianna, Shaffer Lynn, Fannin Elizabeth, Burgers John, Poll Wayne, Ward Eric S, Banks Kevin, Bell Jeffrey G

机构信息

Ohio State University College of Medicine, Columbus, Ohio, USA.

出版信息

JSLS. 2011 Apr-Jun;15(2):193-9. doi: 10.4293/108680811X13022985131930.

DOI:10.4293/108680811X13022985131930
PMID:21902974
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3148870/
Abstract

OBJECTIVES

This study describes the early experience of robotic prostatectomy exclusively at a teaching community hospital.

METHODS

This is a retrospective report of 153 consecutive patients on whom 4 physicians were the operating surgeon.

RESULTS

The average hospital stay was 1.5 days, the mean operative time was 175 minutes, and the estimated operative blood loss was <300mL. The perioperative complication rate was 7.8% (12/153). The prostate-specific antigen failure rate was 2% (2/114). Urinary continence was maintained in 98% of patients 9 months after surgery. Postoperative Gleason scores differed significantly from preoperative biopsy results (P<0.001). Pathological records reported positive margins in 35% (54/153) of specimens. T3 tumors had positive margins more than twice as often as T2 tumors (P<0.002). Surgeon experience correlated with shorter operative times (P=0.001), but not with positive margins. Increasing body mass index was associated with increased operating time (P<0.001).

CONCLUSIONS

Robotic prostatectomy appears to be a safe and successful option for prostate cancer treatment in a teaching community hospital.

摘要

目的

本研究描述了仅在一家教学社区医院开展机器人前列腺切除术的早期经验。

方法

这是一项对153例连续患者的回顾性报告,手术由4名医生担任主刀。

结果

平均住院时间为1.5天,平均手术时间为175分钟,估计手术失血量<300mL。围手术期并发症发生率为7.8%(12/153)。前列腺特异性抗原失败率为2%(2/114)。98%的患者术后9个月保持尿失禁。术后Gleason评分与术前活检结果有显著差异(P<0.001)。病理记录显示35%(54/153)的标本切缘阳性。T3期肿瘤切缘阳性的发生率是T2期肿瘤的两倍多(P<0.002)。术者经验与较短的手术时间相关(P=0.001),但与切缘阳性无关。体重指数增加与手术时间延长相关(P<0.001)。

结论

在教学社区医院,机器人前列腺切除术似乎是治疗前列腺癌的一种安全且成功的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fe3/3148870/8822839c9834/jls0021127150004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fe3/3148870/b263681d1cb6/jls0021127150001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fe3/3148870/ccb5f6d99bd8/jls0021127150002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fe3/3148870/ecfb54fa0c7d/jls0021127150003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fe3/3148870/8822839c9834/jls0021127150004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fe3/3148870/b263681d1cb6/jls0021127150001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fe3/3148870/ccb5f6d99bd8/jls0021127150002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fe3/3148870/ecfb54fa0c7d/jls0021127150003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fe3/3148870/8822839c9834/jls0021127150004.jpg

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本文引用的文献

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JSLS. 2010 Jan-Mar;14(1):1-5. doi: 10.4293/108680810X12674612014266.
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The impact of positive surgical margins on mortality following radical prostatectomy during the prostate specific antigen era.在 PSA 时代根治性前列腺切除术后阳性切缘对死亡率的影响。
J Urol. 2010 Mar;183(3):1003-9. doi: 10.1016/j.juro.2009.11.039. Epub 2010 Jan 21.
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"Learning curve" may not be enough: assessing the oncological experience curve for robotic radical prostatectomy.
“学习曲线”可能还不够:评估机器人根治性前列腺切除术的肿瘤学经验曲线。
J Endourol. 2010 Mar;24(3):473-7. doi: 10.1089/end.2009.0121.
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Impact of positive surgical margins after radical prostatectomy differs by disease risk group.根治性前列腺切除术后切缘阳性的影响因疾病风险组而异。
J Urol. 2010 Jan;183(1):145-50. doi: 10.1016/j.juro.2009.08.132.
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Prostate volume and the incidence of extraprostatic extension: is there a relation?前列腺体积与前列腺外侵犯的发生率:二者有关联吗?
J Endourol. 2009 Mar;23(3):383-6. doi: 10.1089/end.2008.0247.
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Are positive surgical margins in radical prostatectomy specimens an independent prognostic marker?根治性前列腺切除标本中的手术切缘阳性是一个独立的预后标志物吗?
Scand J Urol Nephrol. 2008;42(6):514-21. doi: 10.1080/00365590802299585.
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