Haq Muhammad Wasif, Batool Mehwish, Ahsan Syed Hammad, Sharma Gaurav
Department of Periodontology, Liaquat College of Medicine & Dentistry, Karachi, Pakistan.
Gen Dent. 2011 May-Jun;59(3):e110-5.
The aim of this study was to evaluate and compare the efficacy of antiplaque mouthwashes. Plaque levels were determined by applying a plaque-disclosing solution using the Turesky et al modification of the Quigley Hein plaque index. The control group (n = 6) brushed twice per day with fluoride toothpaste for one minute and rinsed with water, while the study groups (n = 6) brushed once per day with fluoride toothpaste for one minute, followed by rinsing with 5.0 mL of mouthwash diluted with 10.0 mL of water for 30 seconds. The control group brushed and rinsed with water twice per day. The results indicated that cetylpyridinium chloride in combination with sodium fluoride offered maximum plaque inhibition, followed by chlorhexidine gluconate and sodium monofluorophosphate, while plaque levels increased in the control group and with the combination of chlorhexidine gluconate and sodium fluoride. The only antiplaque agents to demonstrate a statistically significant difference from the control were cetylpyridinium chloride in combination with sodium fluoride, and chlorhexidine gluconate. Increasing the fluoride concentration had no impact on antiplaque activity.
本研究的目的是评估和比较抗牙菌斑漱口水的疗效。通过使用经图雷斯基等人修改的奎格利-海因菌斑指数应用菌斑显示溶液来确定菌斑水平。对照组（n = 6）每天用含氟牙膏刷牙两次，每次一分钟，然后用水漱口；而研究组（n = 6）每天用含氟牙膏刷牙一次，每次一分钟，随后用5.0毫升漱口水与10.0毫升水稀释后漱口30秒。对照组每天刷牙并用水漱口两次。结果表明，十六烷基氯化吡啶与氟化钠联合使用时对菌斑的抑制作用最强，其次是葡萄糖酸洗必泰及单氟磷酸钠，而对照组以及葡萄糖酸洗必泰与氟化钠联合使用时菌斑水平有所增加。与对照组相比，唯一显示出统计学显著差异的抗牙菌斑剂是十六烷基氯化吡啶与氟化钠联合使用以及葡萄糖酸洗必泰。增加氟浓度对抗牙菌斑活性没有影响。
