Current status of potential bisphenol toxicity in dentistry.

Bisphenols are chemical components found in dental composites and sealants. Similar compounds also can be found in baby bottles, food can liners, and even drinking water. Bisphenols have gained attention recently because they, like other natural and synthetic compounds, including hormone-based drugs and soybean products, have the capacity to mimic the actions of the hormone estrogen in living cells and animals. Such estrogenic activity has been linked to a variety of health problems, including breast and prostate cancer, metabolic disorders, and reproductive dysfunction. In early 2010, the FDA issued a report stating that there are some concerns about the safety of bisphenols in food products and called for more research on bisphenol toxicity. At present, no regulatory or professional organization has expressed concern about health effects of bisphenols in dental materials.