Truelove Edmond L, Dean David, Maltby Samuel, Griffith Matthew, Huggins Kimberly, Griffith Mickealla, Taylor Stuart
Department of Oral Medicine, University of Seattle, WA, USA.
Gen Dent. 2011 Jul-Aug;59(4):281-9; quiz 290-1, 319-20.
The purpose of this investigation was to determine the value of adding narrow band (light) imaging (NBI) to the standard oral soft tissue examination process used to detect mucosal change. A total of 620 dental patients who came to the clinic for regular dental evaluation or for treatment of acute dental problems were given a standard oral soft tissue examination by dental students under faculty supervision. The results of the white light examination were recorded after the tissues were examined with NBI, at which point areas with a loss of fluorescence (LOF) were recorded. The nature of the tissue change was classified clinically as normal variation, inflammatory, traumatic, dysplastic, or other, and patients were categorized depending on their clinical findings: normal, need follow-up visit, or immediate biopsy. Risk factors related to oral dysplasia also were recorded. The addition of NBI added between one and two minutes to the examination process. Of the 620 examinations, an area with an LOF suggestive of pathology was detected in 69 subjects (11.1%). After a second immediate evaluation, 28 of the 69 subjects were scheduled for follow-up or biopsy. None of the lesions discovered in these 28 subjects had been detected using standard (white light) examination. Adding NBI to the routine clinical examination resulted in detection of changes not seen with white light examination in 11.1% of patients; of these, a small but important number were found to have otherwise undetected persistent changes representing inflammatory lesions or potentially dangerous oral dysplasia. Adding NBI as an adjunctive diagnostic procedure improved the quality and outcome of the examination process.
本研究的目的是确定在用于检测黏膜变化的标准口腔软组织检查过程中增加窄带（光）成像（NBI）的价值。共有620名因定期牙科评估或治疗急性牙科问题前来诊所的牙科患者，在教员监督下由牙科学生进行了标准口腔软组织检查。在用NBI检查组织后记录白光检查的结果，此时记录荧光丧失（LOF）区域。将组织变化的性质临床分类为正常变异、炎症、创伤、发育异常或其他，并根据患者的临床发现进行分类：正常、需要随访或立即活检。还记录了与口腔发育异常相关的危险因素。添加NBI使检查过程增加了1至2分钟。在620次检查中，69名受试者（11.1%）检测到提示病变的LOF区域。在第二次即时评估后，69名受试者中的28名被安排进行随访或活检。在这28名受试者中发现的病变，使用标准（白光）检查均未检测到。在常规临床检查中添加NBI，导致11.1%的患者检测到白光检查未发现的变化；其中，有一小部分但数量可观的患者被发现存在未被检测到的持续性变化，这些变化代表炎症性病变或潜在危险的口腔发育异常。添加NBI作为辅助诊断程序可提高检查过程的质量和结果。
