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大脑脑桥内皮质脊髓束的解剖位置和体感觉排列。

Anatomic location and somatotopic arrangement of the corticospinal tract at the cerebral peduncle in the human brain.

机构信息

Department of Physical Therapy, Daegu University, Daegu, Republic of Korea.

出版信息

AJNR Am J Neuroradiol. 2011 Dec;32(11):2116-9. doi: 10.3174/ajnr.A2660. Epub 2011 Sep 8.

DOI:10.3174/ajnr.A2660
PMID:21903908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7964417/
Abstract

BACKGROUND AND PURPOSE

Little is known about the detailed anatomic location and somatotopic arrangement at the CP. Using DTT with FSL tools, we conducted an investigation of the anatomic location and somatotopic arrangement of the CST at the CP in the human brain.

MATERIALS AND METHODS

We recruited 43 healthy volunteers for this study. DTI was obtained by using 1.5T, and CSTs for the hand and leg were obtained by using the FSL tool. The somatotopic location of the CST was evaluated as the highest probabilistic location at the upper and lower midbrain. The posterior boundary was determined as the line between the interpeduncular fossa and the lateral sulcus; we then drew a rectangle on the basis of the boundary of the CP.

RESULTS

In the mediolateral direction, the highest probabilistic locations for the hand and leg were an average of 60.46% and 69.98% from the medial boundary at the upper midbrain level and 53.44% and 62.76% at the lower midbrain level, respectively. As for the anteroposterior direction, the highest probabilistic locations for the hand and leg were an average of 28.26% and 32.03% from the anterior boundary at the upper midbrain level and 30.19% and 33.59% at the lower midbrain level, respectively.

CONCLUSIONS

We found that the hand somatotopy for the CST is located at the middle portion of the CP and the leg somatotopy is located lateral to the hand somatotopy.

摘要

背景与目的

对于 CP 处 CST 的详细解剖位置和体感觉分布尚不清楚。本研究采用 DTT 联合 FSL 工具,旨在探讨人脑 CP 处 CST 的解剖位置和体感觉分布。

材料与方法

本研究共纳入 43 名健康志愿者。采用 1.5T 磁共振扫描仪进行弥散张量成像(DTI),使用 FSL 工具获取手和腿的 CST。通过 CST 在手和腿运动皮质的最高概率位置评估其体感觉位置,该位置位于中脑上、下水平的内侧边界外侧 60.46%和 69.98%,以及 53.44%和 62.76%。对于前后方向,手和腿的 CST 在中脑上、下水平的前边界外侧 28.26%和 32.03%,以及前边界内侧 30.19%和 33.59%。

结果

在 CST 手和腿的体感觉分布中,手的体感位置位于 CP 的中间部分,而腿的体感位置位于手的体感位置外侧。

结论

我们发现 CST 的手体感区位于 CP 的中部,而腿体感区位于手体感区的外侧。

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本文引用的文献

1
Somatotopic arrangement of the corticospinal tract at the medullary pyramid in the human brain.人脑延髓锥体的皮质脊髓束的体节排列。
Eur Neurol. 2011;65(1):46-9. doi: 10.1159/000323022. Epub 2011 Jan 4.
2
Location of the corticospinal tract at the corona radiata in human brain.大脑皮质脊髓束在放射冠的位置。
Brain Res. 2010 Apr 22;1326:75-80. doi: 10.1016/j.brainres.2010.02.050. Epub 2010 Feb 25.
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Somatotopic location of corticospinal tract at pons in human brain: a diffusion tensor tractography study.人脑桥脑皮质脊髓束的体素定位:一项弥散张量纤维束成像研究。
Neuroimage. 2010 Jul 1;51(3):952-5. doi: 10.1016/j.neuroimage.2010.02.063. Epub 2010 Mar 4.
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Evaluation of the somatotopic organization of corticospinal tracts in the internal capsule and cerebral peduncle: results of diffusion-tensor MR tractography.内囊和大脑脚皮质脊髓束躯体定位组织的评估:扩散张量磁共振纤维束成像结果
Korean J Radiol. 2008 May-Jun;9(3):191-5. doi: 10.3348/kjr.2008.9.3.191.
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Corticospinal tract location in internal capsule of human brain: diffusion tensor tractography and functional MRI study.皮质脊髓束在人脑内囊的定位:扩散张量纤维束成像与功能磁共振成像研究
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Poststroke cerebral peduncular atrophy correlates with a measure of corticospinal tract injury in the cerebral hemisphere.中风后脑脚萎缩与大脑半球皮质脊髓束损伤程度相关。
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The pyramidal tract has a predictable course through the centrum semiovale: a diffusion-tensor based tractography study.锥体束通过半卵圆中心有可预测的走行:一项基于扩散张量的纤维束成像研究。
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Corticospinal tract asymmetries at the level of the internal capsule: is there an association with handedness?内囊水平的皮质脊髓束不对称性:与利手有关联吗?
Neuroimage. 2007 Aug 15;37(2):379-86. doi: 10.1016/j.neuroimage.2007.05.047. Epub 2007 Jun 7.
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Somatotopy of corticospinal tract in the internal capsule shown by functional MRI and diffusion tensor images.功能磁共振成像和扩散张量成像显示内囊皮质脊髓束的躯体定位
Neuroreport. 2007 May 7;18(7):665-8. doi: 10.1097/WNR.0b013e3280d943e1.
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Probabilistic diffusion tractography with multiple fibre orientations: What can we gain?具有多种纤维取向的概率性扩散张量成像:我们能获得什么?
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