Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Republic of Korea.
Neurosci Lett. 2012 Aug 15;523(2):111-4. doi: 10.1016/j.neulet.2012.06.053. Epub 2012 Jun 28.
Little is known about the somatotopic location of the corticospinal tract (CST) in the centrum semiovale (CS). We investigated the somatotopic location of the CST in the CS in the human brain using diffusion tensor tractography (DTT). Fifty-two healthy volunteers were recruited for this study. Diffusion tensor images (DTIs) were obtained at 1.5T, and CSTs for the hand and leg were obtained using FMRIB software. Normalized DTT images were reconstructed using the Montreal Neurological Institute echo-planar imaging template supplied with the SPM. Individual DTI data were calculated as number of pixels in the CS. In the mediolateral direction, average distances of the highest probabilistic locations for hand and leg somatotopies were 25.57 mm and 21.72 mm from the midline between the right and left hemispheres, respectively. For the anteroposterior direction, the average distance of the highest probabilistic locations for hand and leg somatotopies were 0.4 mm and 5.2 mm behind the horizontal line between the medial end of the central sulcus and midline, respectively. In conclusion, hand somatotopy of the CST was found to be located at about 26 mm lateral to the midline almost along the horizon line between the medial end of central sulcus and midline, and leg somatotopy of the CST was found to be located medioposteriorly to the hand somatotopy of the CST.
关于皮质脊髓束（CST）在半卵圆中心（CS）中的体感觉定位，目前知之甚少。我们使用弥散张量纤维束成像（DTT）研究了人类大脑 CS 中 CST 的体感觉定位。这项研究招募了 52 名健康志愿者。在 1.5T 下获得弥散张量图像（DTI），并使用 FMRIB 软件获得手和腿的 CST。使用 SPM 提供的蒙特利尔神经学研究所回波平面成像模板重建归一化 DTT 图像。个体 DTI 数据计算为 CS 中的像素数。在中外侧方向，手和腿体感拓扑的最高概率位置的平均距离分别为距右侧和左侧大脑半球中线 25.57mm 和 21.72mm。在前后方向，手和腿体感拓扑的最高概率位置的平均距离分别为中央沟内侧末端与中线之间的水平线后面 0.4mm 和 5.2mm。总之，CST 的手体感定位被发现位于中线约 26mm 外侧，几乎沿着中央沟内侧末端与中线之间的水平线上，而 CST 的腿体感定位被发现位于 CST 的手体感定位的中后部。
