University of Florida, Gainesville, FL 32610, USA.
J Perinatol. 2012 Mar;32(3):205-9. doi: 10.1038/jp.2011.78. Epub 2011 Sep 8.
The purpose of this randomized pilot study was to collect preliminary data regarding the feasibility and effects of early initiation of milk expression on the onset of lactogenesis stage II and milk volume in mothers of very low birth weight (VLBW) infants.
Twenty women were randomized to initiate milk expression within 60 min (group 1) or 1 to 6 h (group 2) following delivery. Milk volume and timing of lactogenesis stage II was compared between groups using Wilcoxon's rank sum tests.
Group 1 produced statistically significantly more milk than group 2 during the first 7 days (P=0.05) and at week 3 (P=0.01). Group 1 also demonstrated a significantly earlier lactogenesis stage II (P=0.03).
Initiation of milk expression within 1 h following delivery increases milk volume and decreases time to lactogenesis stage II in mothers of VLBW infants.
本随机初步研究旨在收集关于早发性乳汁分泌对极低出生体重（VLBW）婴儿母亲泌乳二期开始和乳汁量的影响的初步数据。
20 名女性随机分为分娩后 60 分钟内（第 1 组）或 1-6 小时内（第 2 组）开始乳汁分泌。使用 Wilcoxon 秩和检验比较两组之间的乳汁量和泌乳二期的时间。
第 1 组在第 1 天至第 7 天（P=0.05）和第 3 周（P=0.01）的产奶量明显多于第 2 组。第 1 组的泌乳二期也明显更早（P=0.03）。
分娩后 1 小时内开始乳汁分泌可增加 VLBW 婴儿母亲的乳汁量并减少泌乳二期的时间。
