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迈向也门血吸虫病的全国控制:扩大全社区治疗的试点项目。

Towards nationwide control of schistosomiasis in Yemen: a pilot project to expand treatment to the whole community.

机构信息

Ministry of Public Health and Population, Al Hasaba, PO Box 543, Sana'a, Republic of Yemen.

出版信息

Trans R Soc Trop Med Hyg. 2011 Nov;105(11):617-27. doi: 10.1016/j.trstmh.2011.07.013. Epub 2011 Sep 9.

DOI:10.1016/j.trstmh.2011.07.013
PMID:21907376
Abstract

Both the urinary and intestinal forms of schistosomiasis are thought to be widespread in the Republic of Yemen, with estimates of 3 million people infected and 600 000 suffering clinical morbidity. Sub-national control has been ongoing since 2006 via the distribution of praziquantel (PZQ) against schistosomiasis and albendazole (ALB) against soil-transmitted helminths using school-based treatment. In preparation for a 6-year nationwide control programme with the aim of expanding treatment to the wider community, a new programmatic approach of complementing school-based distribution with community-based treatment was trialled in 10 highly endemic districts in three governorates in December 2009. The new approach achieved coverage of 90.1% of non-enrolled children: a 40% increase compared with the same districts in 2008, and coverage of 97.9% of enrolled children: a 2% increase compared to 2008. Coverage of females (children and adults) was 81.8%, and of adults in general was 73.9%. The total cost per person treated was US$0.66 (US$0.79 in 2008), which includes training, health education, social mobilization, distribution and drugs. These results provide hope that a combined school and community-based approach can be successfully implemented on a wider scale during the main control programme in 2010-2015, with approximately 10 million people targeted in the first year alone.

摘要

在也门共和国,人们认为有尿路和肠道两种类型的血吸虫病广泛存在,估计有 300 万人感染,60 万人患有临床疾病。自 2006 年以来,通过在学校分发吡喹酮(PZQ)治疗血吸虫病和阿苯达唑(ALB)治疗土壤传播的蠕虫,一直在进行分区域控制。为了筹备一项为期六年的全国控制规划,目的是将治疗范围扩大到更广泛的社区,在 2009 年 12 月,三个省的 10 个高度流行地区试用了一种新的规划方法,即补充以学校为基础的分发,开展以社区为基础的治疗。新方法的覆盖率达到了 90.1%的非入学儿童:与 2008 年相比,增加了 40%,入学儿童的覆盖率达到了 97.9%:与 2008 年相比,增加了 2%。女性(儿童和成人)的覆盖率为 81.8%,一般成人的覆盖率为 73.9%。每人治疗费用为 0.66 美元(2008 年为 0.79 美元),包括培训、健康教育、社会动员、分发和药物。这些结果表明,在 2010-2015 年的主要控制规划期间,以学校和社区为基础的综合方法可以在更大范围内成功实施,仅在第一年就有大约 1000 万人成为目标人群。

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