Khleif Aroub A, Rodriguez Nidra, Brown Deborah, Escobar Miguel A
Department of Pediatrics and Gulf States Hemophilia & Thrombophilia Center, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
J Aging Res. 2011;2011:985703. doi: 10.4061/2011/985703. Epub 2011 Sep 7.
Introduction. Advances in hemophilia care and treatment have led to increases in the life expectancy among hemophiliacs. As a result, persons with hemophilia are reaching an older age and experiencing various age-related health conditions never seen before in this population. Aim. To determine the prevalence of comorbidities among middle-aged and elderly hemophilia A and hemophilia B patients. Methods. Retrospective chart review among all hemophilia patients, who attended the Gulf States Hemophilia and Thrombophilia Center. Results. All patients had at least one comorbid condition other than hemophilia, and the majority had between 3 and 6 comorbidities. The most common conditions identified were chronic hepatitis C, hypertension, HIV, chronic arthropathy, and overweight/obesity. Conclusions. Since persons with comorbidities are more likely to have poorer health outcomes and require greater care in managing their health needs, caring for aging hemophiliacs is likely to pose various social and economic challenges for both patients and providers.
引言。血友病护理和治疗方面的进展使血友病患者的预期寿命有所提高。因此，血友病患者的年龄越来越大，并出现了该人群以前从未见过的各种与年龄相关的健康状况。目的。确定中老年甲型和乙型血友病患者中合并症的患病率。方法。对所有前往海湾国家血友病和血栓形成中心就诊的血友病患者进行回顾性病历审查。结果。所有患者除血友病外至少有一种合并症，大多数患者有3至6种合并症。确定的最常见病症为慢性丙型肝炎、高血压、艾滋病毒、慢性关节病和超重/肥胖。结论。由于合并症患者更有可能出现较差的健康结果，并且在管理其健康需求方面需要更多护理，因此照顾老年血友病患者可能会给患者和医疗服务提供者带来各种社会和经济挑战。
