Warren Alpert School of Medicine at Brown University, Miriam Hospital, 164 Summit Ave, Providence, RI 02906, USA.
BMC Public Health. 2011 Sep 14;11:701. doi: 10.1186/1471-2458-11-701.
The experiences of the past 10 years have shown that it is feasible to treat HIV infected patients with ART even in severely resource constrained settings. Achieving the levels of antiretroviral coverage necessary to impact the course of the HIV epidemic remains a challenge and antiretroviral therapy coverage in most nations remains short of even current recommendations. Though treatment as prevention and seek, test, treat and retain strategies are attractive, realization of the benefits of these strategies will require the ability to successfully engage key hard to reach populations such as sex workers. The successes engaging these populations in research settings as seen in the article by Huet et al are encouraging, however key questions remain regarding the sustainability of these efforts as patients are transitioned back to national HIV control programs, many of which are struggling even to maintain the current panels in care in the face declining external funding for HIV care. To achieve the critical goals of increasing treatment uptake and retention and thereby curtail the epidemic of HIV, advocacy from both medicine and public health providers will be critical to generate the support and political will necessary to sustain and enhance the necessary HIV care programs worldwide.
过去 10 年的经验表明,即使在资源严重受限的环境下,使用抗逆转录病毒疗法(ART)治疗 HIV 感染者也是可行的。然而,要实现对 HIV 流行进程产生影响所需的抗逆转录病毒药物覆盖水平仍然是一个挑战,大多数国家的抗逆转录病毒药物覆盖率甚至还未达到当前的建议水平。尽管治疗即预防、发现即检测、检测即治疗和治疗即保持策略具有吸引力,但要实现这些策略的效益,就需要有能力成功接触到难以接触的关键人群,如性工作者。正如 Huet 等人的文章所表明的,在研究环境中成功接触这些人群是令人鼓舞的,然而,这些努力的可持续性仍然存在关键问题,因为当患者被转回国家 HIV 控制项目时,许多项目甚至难以维持目前的护理小组,因为 HIV 护理的外部资金不断减少。为了实现增加治疗覆盖率和保留率的关键目标,从而遏制 HIV 流行,医学和公共卫生提供者的宣传将是至关重要的,以产生必要的支持和政治意愿,从而在全球范围内维持和加强必要的 HIV 护理项目。