雷米普利治疗期间出现严重低钠血症。
Severe hyponatraemia during therapy with ramipril.
作者信息
Ramasamy I
机构信息
Royal Worcester Hospital, Charles Hastings Way, Worcester, Worcester, G75 8RG, UK.
出版信息
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.06.2009.1932. Epub 2009 Sep 15.
Abstract
An older patient who was being treated with ramipril, chlorpromazine and aspirin presented with hypotension and serum sodium of 119 mmol/litre. The patient was treated with intravenous saline and all drug therapy was stopped. Serum sodium rose following fluid therapy. Ramipril was restarted as the patient's blood pressure increased. Serum sodium dropped to 112 mmol/litre. The patient's thyroid and adrenal functions were within normal limits, as were liver function tests and C-reactive protein. The hyponatraemia corrected when the patient was placed on fluid restriction and treatment with ramipril stopped.
摘要
一名正在接受雷米普利、氯丙嗪和阿司匹林治疗的老年患者出现低血压，血清钠为119毫摩尔/升。该患者接受了静脉输注生理盐水治疗，所有药物治疗均停止。液体治疗后血清钠升高。随着患者血压升高，重新开始使用雷米普利。血清钠降至112毫摩尔/升。患者的甲状腺和肾上腺功能在正常范围内，肝功能检查和C反应蛋白也是如此。当患者进行液体限制并停止使用雷米普利治疗时，低钠血症得到纠正。
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