Pole Cardiovasculaire et Thoracique, Clinique de Cardiologie, Hôpital A. Michallon, Grenoble, France.
Clin Transplant. 2012 May-Jun;26(3):484-8. doi: 10.1111/j.1399-0012.2011.01525.x. Epub 2011 Sep 15.
Extracorporeal life support (ECLS) represents an effective, emergent therapy for patients with end-stage heart failure or cardiac arrest. However, ECLS is typically not used as a bridge to heart transplantation because of the limited duration of ECLS. In France, high-urgency priority heart transplantation remains a possibility for transplant patients who are on ECLS. In this article, we present our experience with high-urgency priority heart transplantation after ECLS. From July 2004 to December 2009, 242 patients underwent emergent ECLS. Heart transplantation was performed in eight of these patients. Time of ECLS was 6.3 ± 4.6 d. Before heart transplantation, all patients on ECLS had decreased organ dysfunctions and four were conscious. Despite frequent post-operative complications, no death occurred during the first year after transplantation. In our experience, ECLS is a valid method of supporting patients awaiting high-urgency heart transplantation and can be used as a short-term bridge to heart transplantation.
体外生命支持（ECLS）是治疗终末期心力衰竭或心脏骤停患者的一种有效、紧急治疗方法。然而，由于 ECLS 的持续时间有限，通常不将其用作心脏移植的桥接治疗。在法国，对于接受 ECLS 的移植患者，高紧急优先级心脏移植仍然是一种可能。本文介绍了我们在 ECLS 后进行高紧急优先级心脏移植的经验。自 2004 年 7 月至 2009 年 12 月，242 例患者接受了紧急 ECLS。在这 242 例患者中，有 8 例接受了心脏移植。ECLS 的时间为 6.3 ± 4.6 d。在心脏移植前，所有接受 ECLS 的患者的器官功能均有不同程度的改善，其中 4 例患者意识清醒。尽管术后并发症频繁，但移植后第一年无死亡病例发生。根据我们的经验，ECLS 是支持等待高紧急心脏移植患者的有效方法，可作为心脏移植的短期桥接治疗。
