Lan Hai, Nishitani Hiromu, Nishihara Sadamitsu, Ueno Junji, Takao Shoichiro, Iwamoto Seiji, Kawanaka Takashi, Mahmut Mawlan, Qingge Si
Department of Radiology, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan.
J Med Invest. 2011 Aug;58(3-4):175-9. doi: 10.2152/jmi.58.175.
The purpose of this study was to evaluate the usefulness of thick slab minimum intensity projection (MinIP) as a follow-up method in patients with pulmonary emphysema. This method was used to determine the presence or absence of changes over time in the lung field based on multi-detector-row CT (MDCT) data.
Among patients diagnosed with pulmonary emphysema who underwent 16-MDCT (slice thickness, 1 mm) twice at an interval of 6 months or more, 12 patients without changes in the lung field and 14 with clear changes in the lung field were selected as subjects. An image interpretation experiment was performed by five image interpreters. Pulmonary emphysema was followed up using two types of thick slab MinIP (thick slab MinIP 1 and 2) and multi-planar reformation (MPR), and the results of image interpretation were evaluated by receiver operating characteristic (ROC) analysis. In addition, the time required for image interpretation was compared among the three follow-up methods.
The area under the ROC curve (Az) was 0.794 for thick slab MinIP 1, 0.778 for the thick slab MinIP 2, and 0.759 for MPR, showing no significant differences among the three methods. Individual differences in each item were significantly more marked for MPR than for thick slab MinIP. The time required for image interpretation was around 18 seconds for thick slab MinIP 1, 11 seconds for thick slab MinIP 2, and approximately 127 seconds for MPR, showing significant differences among the three methods.
There were no significant differences in the results of image interpretation regarding the presence or absence of changes in the lung fields between thick slab MinIP and MPR. However, thick slab MinIP showed a shorter image interpretation time and smaller individual differences in the results among image interpreters than MPR, suggesting the usefulness of this method for determining the presence or absence of changes with time in the lung fields of patients with pulmonary emphysema.
本研究旨在评估厚层最小密度投影(MinIP)作为肺气肿患者随访方法的实用性。该方法用于根据多排探测器CT(MDCT)数据确定肺野随时间的变化情况。
在间隔6个月或更长时间接受两次16层MDCT(层厚1mm)检查的肺气肿患者中,选取12例肺野无变化和14例肺野有明显变化的患者作为研究对象。由5名影像解读人员进行图像解读实验。采用两种厚层MinIP(厚层MinIP 1和2)和多平面重组(MPR)对肺气肿进行随访,并通过受试者操作特征(ROC)分析评估图像解读结果。此外,比较了三种随访方法的图像解读所需时间。
厚层MinIP 1的ROC曲线下面积(Az)为0.794,厚层MinIP 2为0.778,MPR为0.759,三种方法之间无显著差异。MPR各项的个体差异明显大于厚层MinIP。厚层MinIP 1的图像解读时间约为18秒,厚层MinIP 2为11秒,MPR约为127秒,三种方法之间存在显著差异。
厚层MinIP和MPR在肺野变化情况的图像解读结果上无显著差异。然而,与MPR相比,厚层MinIP的图像解读时间更短,影像解读人员之间结果的个体差异更小,这表明该方法在确定肺气肿患者肺野随时间变化情况方面具有实用性。