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匈牙利鸽圆环病毒的遗传多样性

Genetic diversity of pigeon circovirus in Hungary.

作者信息

Cságola Attila, Lorincz Márta, Tombácz Kata, Wladár Zsófia, Kovács Eszter, Tuboly Tamás

机构信息

Department of Microbiology and Infectious Diseases, Szent István University, Hungária krt. 23-25, Budapest 1143, Hungary.

出版信息

Virus Genes. 2012 Feb;44(1):75-9. doi: 10.1007/s11262-011-0669-6. Epub 2011 Sep 16.

Abstract

Pigeon circoviruses (PiCV) had been identified worldwide and are responsible for immune suppression and a variety of diseases collectively referred to as young pigeon disease syndrome. Samples from racing pigeons were collected throughout Hungary and analyzed for the presence of PiCV by polymerase chain reaction. The capsid protein coding gene was amplified from ten PiCVs of different origins, and compared with known PiCV sequences. The results indicated that PiCV was highly variable, the viruses formed five distinct genetic groups. Differences of the 3' end of the gene suggested the possibility of genetic recombination among these groups.

摘要

鸽圆环病毒(PiCV)已在全球范围内被鉴定出来,它会导致免疫抑制以及一系列统称为幼鸽病综合征的疾病。在匈牙利全国范围内收集了赛鸽样本,并通过聚合酶链反应分析其中是否存在PiCV。从10株不同来源的PiCV中扩增出衣壳蛋白编码基因,并与已知的PiCV序列进行比较。结果表明,PiCV具有高度变异性,这些病毒形成了五个不同的遗传组。基因3'端的差异表明这些组之间可能发生了基因重组。

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