Department of Clinical and Theoretical Mental Health, Faculty of Medicine, Kutvolgyi Clinical Center, Semmelweis University, Kutvolgyi u 4, Budapest H-1125, Hungary.
Med Hypotheses. 2011 Dec;77(6):1048-50. doi: 10.1016/j.mehy.2011.08.045. Epub 2011 Sep 15.
The persistent use of different forms of nicotine replacement therapy (NRT) is an under-investigated issue in medical research. While the data concerning the proportion of long-term users in the population of total NRT users seems reassuring at first glance, we must recognize that the small relative numbers (proportions) conceal a population of persistent NRT users with a considerable absolute number of members. Furthermore, only a small amount of data is available concerning the safety of persistent NRT use. At the present time we therefore have no basis for declaring that the population of long-term users are under cover (we are only able to state that persistent use of NRT is undoubtedly safer than the continuation of smoking). Consequently, there is a need to conduct large-scale studies with the primary aim of monitoring for misuse of OTC NRT and assessing the possible physical and mental health risks of persistent NRT use.
持续使用不同形式的尼古丁替代疗法（NRT）在医学研究中是一个研究不足的问题。虽然关于长期使用者在 NRT 总使用者中的比例的数据乍一看似乎令人安心，但我们必须认识到，小的相对数量（比例）掩盖了一个具有相当数量成员的持续使用 NRT 的人群。此外，关于持续使用 NRT 的安全性的数据非常有限。因此，目前我们没有理由宣称长期使用者群体是安全的（我们只能说持续使用 NRT 无疑比继续吸烟更安全）。因此，有必要进行大规模研究，主要目的是监测非处方 NRT 的滥用情况，并评估持续使用 NRT 可能带来的身心健康风险。
