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胎儿脑室扩大:产后管理

Fetal ventriculomegaly: postnatal management.

作者信息

Wang Kyu-Chang, Lee Ji Yeoun, Kim Seung-Ki, Phi Ji Hoon, Cho Byung-Kyu

机构信息

Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, 101 Daehak-ro, Jongno-gu, Seoul 110-769, South Korea.

出版信息

Childs Nerv Syst. 2011 Oct;27(10):1571-3. doi: 10.1007/s00381-011-1556-0. Epub 2011 Sep 17.

Abstract

INTRODUCTION

It is the current status of fetal ventriculomegaly that although the technology for diagnosis is advanced, it does not have significant impact on the management outcome. Fetal ventriculomegaly is mainly treated after birth.

METHODS

We reviewed the literature and suggested policies of postnatal evaluation and surgical management of fetal hydrocephalus. Our experience of 44 cases of fetal ventriculomegaly diagnosed by fetal ultrasonography, in which major poor prognostic factors were absent and for which prenatal pediatric neurosurgical consultation was sought, was also presented.

RESULTS

Our experience showed etiologic heterogeneity of fetal ventriculomegaly although our cases seemed to be surgical candidates more likely than whole group of fetal ventriculomegaly. There were limitations in prenatal evaluation of fetal hydrocephalus. The first step for postnatal management is etiologic classification. It should be clarified after birth whether there is remarkable disturbance of cerebrospinal fluid dynamics or not. The rate of postnatal progression of ventricular dilatation is also important for the decision of treatment plan. For surgical treatment in very young children, special considerations should be paid on technical feasibility, rate of postoperative infection or malfunction, prevention of rapidly developing nervous system from the possible damage, and great plasticity of young brain.

CONCLUSION

Indication, methods, and timing of surgical treatment must be individually tailored according to the etiology, degree and rate of progression of ventriculomegaly, and patient's age when surgical treatment is considered.

摘要

引言

胎儿脑室扩大的现状是,尽管诊断技术先进,但对治疗结果并无显著影响。胎儿脑室扩大主要在出生后进行治疗。

方法

我们回顾了文献,并提出了胎儿脑积水出生后评估及手术治疗的策略。我们还介绍了通过胎儿超声诊断出的44例胎儿脑室扩大病例的经验,这些病例不存在主要的不良预后因素,且已寻求产前儿科神经外科会诊。

结果

我们的经验表明,胎儿脑室扩大存在病因异质性,尽管我们的病例似乎比整个胎儿脑室扩大组更有可能成为手术候选者。胎儿脑积水的产前评估存在局限性。出生后管理的第一步是病因分类。出生后应明确脑脊液动力学是否存在明显紊乱。脑室扩张的出生后进展速度对于治疗方案的决策也很重要。对于非常年幼的儿童进行手术治疗时,应特别考虑技术可行性、术后感染或功能障碍发生率、防止快速发育的神经系统受到可能的损害以及幼儿大脑的高度可塑性。

结论

手术治疗的适应症、方法和时机必须根据脑室扩大的病因、程度和进展速度以及考虑手术治疗时患者的年龄进行个体化调整。

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