Unit of Virology, D. Cotugno Hospital, Naples, Italy.
J Cell Physiol. 2012 Jul;227(7):2813-7. doi: 10.1002/jcp.23030.
A novel swine-origin influenza A (H1N1) virus affecting humans was detected in April 2009 in Mexico, Canada, and USA. The S-OIV infection caused a mild to severe febrile respiratory disease throughout the world. Here, we briefly review the main features of influenza A viruses, which caused also other pandemics in the past, and focus in particular on the epidemiology data of the H1N1 influenza in the Italian region Campania, which resulted the most affected by the S-OIV and the one with more lethal cases. In Campania, the peak of influenza preceded of about 2 weeks the incidence peak at the national level. Moreover, the percentage of H1N1-positive patients was much higher in the main town Naples, compared to the other Campania provinces. The age group from 7 months to 17 years was the most affected by the H1N1 infection (43.45%), similarly to what reported at the national level. Here, we discuss the possible reasons of the high H1N1 incidence in Campania and the implications that these findings could have on the future prevention campaigns.
一种新型的猪源甲型 H1N1 流感病毒于 2009 年 4 月在墨西哥、加拿大和美国被发现。这种 S-OIV 感染在全球范围内引起了轻度至重度发热性呼吸道疾病。在这里，我们简要回顾了过去也曾引起其他大流行的甲型流感病毒的主要特征，并特别关注了意大利坎帕尼亚地区 H1N1 流感的流行病学数据，该地区是受 S-OIV 影响最严重、致死病例最多的地区。在坎帕尼亚，流感的高峰期比全国水平的发病率高峰期提前了约 2 周。此外，与坎帕尼亚其他省份相比，在主要城镇那不勒斯，H1N1 阳性患者的比例要高得多。7 个月至 17 岁年龄组受 H1N1 感染的影响最大（43.45%），与全国水平相似。在这里，我们讨论了坎帕尼亚地区 H1N1 发病率高的可能原因，以及这些发现对未来预防活动可能产生的影响。
