Sasajima K, Watanabe M, Takubo K, Takai A, Yamashita K, Onda M
First Department of Surgery, Nippon Medical School, Tokyo, Japan.
Endoscopy. 1990 May;22(3):140-3. doi: 10.1055/s-2007-1012820.
The clinicopathological manifestation of mucoepidermoid carcinoma of the esophagus are reported in two cases. Barium swallow and endoscopy revealed infiltrating and constricting appearances. The tumors were grossly indurated, with or without ulceration. Histologically, the tumors were composed of a mixture of glandular cells which contained signet ring cells and squamous cells. In two cases, the tumor cells invaded into the adventitia, with lymph node metastasis. Two patients died of wide-spread metastasis within 1 year after operation. Our results and previous reports suggest that mucoepidermoid carcinoma of the esophagus is extremely aggressive and has a poor prognosis.
报告了2例食管黏液表皮样癌的临床病理表现。食管吞钡造影和内镜检查显示为浸润性和狭窄性表现。肿瘤大体上质地硬，有或无溃疡形成。组织学上，肿瘤由含有印戒细胞的腺细胞和鳞状细胞混合组成。2例中，肿瘤细胞侵犯至外膜，并伴有淋巴结转移。2例患者术后1年内死于广泛转移。我们的结果和既往报道提示，食管黏液表皮样癌极具侵袭性，预后较差。
