Department of Clinical Radiology, Faculty of Medicine, Kuwait University, Kuwait.
Breast J. 2011 Nov-Dec;17(6):645-50. doi: 10.1111/j.1524-4741.2011.01154.x. Epub 2011 Sep 20.
Granulomatous mastitis (GM) is a recognized, but an uncommon cause of breast mass. Awareness of this condition is important, because it can clinically as well as radiologically mimic breast carcinoma. In this study, we present the imaging features of a series of 10 cases with proved diagnosis of granulomatous mastitis with emphasis on magnetic resonance (MR) findings. All those patients who were histologically proven to have GM of the breast were analyzed. Their files were reviewed and data recorded for demographic, clinical presentation and imaging appearances. The imaging features of the lesions by mammography, ultrasound, and magnetic resonance imaging were analyzed. Of the 305 patients who were surgically treated, 10 (3%) cases proved to have GM. All the patients were females with age ranging from 27 to 53 years (average 38 years and median age 36 years). Guided core biopsy was performed in all cases for confirmation of diagnosis followed by either excision biopsy (in five cases) or lumpectomy (in five cases). The final histopathologic results were chronic granulomatous inflammation consistent with tuberculosis in four cases and GM with acute inflammation, but unknown etiology in four cases and GM due to duct ectasia in two cases. GM, a rare breast condition, should be considered in the differential diagnosis of patients with a breast mass associated with inflammatory change. Routine breast imaging with US, MG, or MRI, the condition from malignant lesions and biopsy, still remains the only method of definite diagnosis.
肉芽肿性乳腺炎（GM）是一种公认的但不常见的乳房肿块原因。了解这种情况很重要，因为它在临床上和影像学上都可以模拟乳腺癌。在这项研究中，我们展示了一系列 10 例经证实的肉芽肿性乳腺炎的影像学特征，重点是磁共振（MR）表现。对所有经组织学证实为乳房 GM 的患者进行了分析。回顾了他们的病历，并记录了人口统计学、临床表现和影像学表现的数据。分析了病变的乳房 X 线摄影、超声和磁共振成像的影像学特征。在接受手术治疗的 305 名患者中，有 10 例（3%）证实为 GM。所有患者均为女性，年龄 27-53 岁（平均 38 岁，中位数年龄 36 岁）。所有病例均行引导芯活检以确诊，随后行切除活检（5 例）或肿块切除术（5 例）。最终的组织病理学结果显示，4 例为符合结核的慢性肉芽肿性炎症，4 例为伴有急性炎症的 GM，但病因不明，2 例为因导管扩张引起的 GM。GM 是一种罕见的乳腺疾病，在鉴别诊断伴有炎症改变的乳腺肿块患者时应考虑到。常规的乳腺成像，包括超声、MG 或 MRI，可以与恶性病变相鉴别，并通过活检进行诊断，但仍然是明确诊断的唯一方法。
