de Araujo Tavares Michel, Dos Santos Marcelo Cordeiro, Monteiro Vinicius da Silva, Almeida Ryan Antônio de Lucena, Flávia Barra do Espirito Santos Alves Pereira Hilka, Botileiro Simone Ferreira de Castro, Oliveira Victor Costa Morais, Vinícius Guimarães de Lacerda Marcus, Vieira René Aloisio da Costa
Programa de Pós-Graduação em Tocoginecologia, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista Júlio de Mesquita Filho, Botucatu, Brazil.
Faculdade de Medicina, Universidade Federal do Amazonas, Manaus, Brazil.
Am J Trop Med Hyg. 2024 Oct 1;111(6):1259-1264. doi: 10.4269/ajtmh.23-0461. Print 2024 Dec 4.
Chronic mastitis varies in etiology between its lactational and nonlactational forms and can be challenging to diagnose. This study aimed to assess the epidemiological profile and diverse etiologies of nonlactational mastitis in Amazonas, Brazil, focusing on distinguishing between tuberculous mastitis (TM) and idiopathic granulomatous mastitis (IGM). This is a retrospective and prospective study that was carried out at the mastitis outpatient clinic of Fundação de Medicina Tropical Doutor Heitor Vieira Dourado from 2013 to 2021 and evaluated epidemiological data, imaging, and laboratory tests. Descriptive statistics were performed. In this retrospective and prospective analysis, 124 medical records were initially considered, with 12 excluded for various reasons. The remaining 112 cases underwent thorough evaluation through epidemiological data, imaging, and laboratory tests, by employing descriptive statistics for analysis. The pathology revealed a predominant prevalence of IGM (64.3%), followed by various forms of mastitis, including confirmed TM (4.5%), presumable TM (8.9%), and others. Our findings indicate that IGM, though a rare cause of breast masses and abscesses, accounts for a significant portion of mastitis cases. Histopathological studies were essential for diagnosis, with ultrasound being the primary imaging tool. This study is one of the largest Brazilian series on nonlactational mastitis, highlighting the condition's complexity and diverse manifestations in the Amazon region.
慢性乳腺炎在哺乳期和非哺乳期的病因有所不同，诊断可能具有挑战性。本研究旨在评估巴西亚马孙州非哺乳期乳腺炎的流行病学特征和多种病因，重点是区分结核性乳腺炎（TM）和特发性肉芽肿性乳腺炎（IGM）。这是一项回顾性和前瞻性研究，于2013年至2021年在热带医学基金会多托·埃托尔·维埃拉·多拉多乳腺炎门诊进行，评估了流行病学数据、影像学和实验室检查结果，并进行了描述性统计分析。在这项回顾性和前瞻性分析中，最初考虑了124份病历，其中12份因各种原因被排除。其余112例通过流行病学数据、影像学和实验室检查进行了全面评估，并采用描述性统计进行分析。病理结果显示IGM占主导地位（64.3%），其次是各种形式的乳腺炎，包括确诊的TM（4.5%）、疑似TM（8.9%）和其他类型。我们的研究结果表明，IGM虽然是乳腺肿块和脓肿的罕见病因，但在乳腺炎病例中占很大比例。组织病理学研究对诊断至关重要，超声是主要的影像学检查工具。本研究是巴西关于非哺乳期乳腺炎的最大系列研究之一，突出了该疾病在亚马孙地区的复杂性和多样表现。
