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妊娠期广泛色素沉着:一例报告。

Extensive hyperpigmentation during pregnancy: a case report.

作者信息

Massinde Anthony, Ntubika Salvatore, Magoma Moke

机构信息

Department of Obstetrics and Gynecology, Bugando Medical Centre, Box 1370, Mwanza, Tanzania.

出版信息

J Med Case Rep. 2011 Sep 19;5:464. doi: 10.1186/1752-1947-5-464.

Abstract

INTRODUCTION

Skin hyperpigmentation is common during pregnancy and often is due to endocrinological changes. Usual patterns include linea nigra, darkening of areola and melasma. We report a rare diffused hyperpigmentation condition in a pregnant woman of dark colored skin.

CASE PRESENTATION

A 19-year-old Tanzanian primigravida at 32 weeks gestation presented at our antenatal clinic concerned about an insidious but progressive onset of unusual darkening of her abdominal skin and both breasts. Her antenatal record was unremarkable except for this unusual onset of abnormal skin color. Findings from her physical examination were unremarkable, and she had a normal blood pressure of 120/70 mmHg. Her abdomen was distended with a uterine fundus of 34 weeks. Almost her entire abdominal skin had darkly colored diffuse deep hyperpigmentation extending cephalad from both iliac fossae to involve both breasts to 2-3 cm beyond the areolae circumferentially. She had a fetus in longitudinal lie and cephalic presentation, with a normal fetal heart rate of 140 beats per minute. Other examination findings were unremarkable. The impression at this stage was exaggerated pigmentation of pregnancy. No medical treatment was offered but she was counseled that she might need medical treatment after delivery. She progressed well and had spontaneous labor and normal delivery at 38 weeks gestation. She was lost to follow up.

CONCLUSION

Unusual pregnancy-related skin hyperpigmentation can occur with no adverse consequences to pregnancy, although may worry a pregnant woman. Reassurance and conservative management may be all that is required to allay a patient's concerns.

摘要

引言

皮肤色素沉着在孕期很常见,通常是由内分泌变化引起的。常见类型包括妊娠黑线、乳晕变黑和黄褐斑。我们报告了一例深色皮肤孕妇出现的罕见弥漫性色素沉着情况。

病例介绍

一名19岁的坦桑尼亚初产妇,妊娠32周,因腹部皮肤和双乳出现隐匿性但进行性加重的异常变黑而到我们的产前诊所就诊。除了这种异常的皮肤颜色变化外,她的产前记录无异常。体格检查结果无异常,血压正常,为120/70 mmHg。她的腹部膨隆,子宫底高度相当于妊娠34周。几乎她整个腹部皮肤都有深色的弥漫性深层色素沉着,从双侧髂窝向上延伸,累及双乳,乳晕周围2 - 3厘米范围内均有色素沉着。胎儿纵产式,头先露,胎心正常,每分钟140次。其他检查结果无异常。此时的诊断印象是妊娠色素沉着加重。未给予药物治疗,但告知她产后可能需要治疗。她进展顺利,妊娠38周时自然临产并顺产。之后失去了随访。

结论

与妊娠相关的异常皮肤色素沉着可能发生,且对妊娠无不良影响,尽管可能会让孕妇担忧。给予安慰和保守处理可能是缓解患者担忧所需要的全部措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c523/3183040/f3940860da98/1752-1947-5-464-1.jpg

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