Dan M, Maximova S, Siegman-Igra Y, Gutman R, Rotmensch H H
Department of Medicine E, E. Wolfson Hospital, Holon, Israel.
Rev Infect Dis. 1990 May-Jun;12(3):537-42. doi: 10.1093/clinids/12.3.537.
The epidemiologic, clinical, and laboratory aspects of group A streptococcal bacteremia were studied in 33 patients seen at two urban hospitals in the Tel Aviv (Israel) area, over an 8-year period. Most patients (two-thirds) were female. Clinically significant bacteremia was observed in 26 patients, two of whom acquired their infection (puerperal sepsis) during hospitalization. A portal of entry, mainly cutaneous, was recognized in 61% of the patients, and a chronic underlying condition was observed in 69%. The case-fatality rate was 27%, with death occurring predominantly in patients admitted with shock or cryptogenic bacteremia. Our clinical experience and literature review show that the presentation of group A streptococcal bacteremia is diverse, with transient bacteremia of uncertain clinical significance on one end of the spectrum and overwhelming sepsis on the other. A practical classification of the various clinical forms of group A streptococcal bacteremia is proposed.
在8年期间，对特拉维夫（以色列）地区两家城市医院收治的33例A组链球菌菌血症患者的流行病学、临床和实验室方面进行了研究。大多数患者（三分之二）为女性。26例患者观察到具有临床意义的菌血症，其中2例在住院期间感染（产褥期败血症）。61%的患者有一个主要为皮肤的感染入口，69%的患者观察到有慢性基础疾病。病死率为27%，死亡主要发生在因休克或隐源性菌血症入院的患者中。我们的临床经验和文献回顾表明，A组链球菌菌血症的表现多种多样，一端是临床意义不确定的短暂菌血症，另一端是暴发性败血症。本文提出了A组链球菌菌血症各种临床形式的实用分类。
