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基于SNOW环形谐振器的光学生物化学传感器。

Optical bio-chemical sensors on SNOW ring resonators.

作者信息

Khorasaninejad Mohammadreza, Clarke Nigel, Anantram M P, Saini Simarjeet Singh

机构信息

Department of Electrical and Computer Engineering, University of Waterloo, Waterloo, Ontario, Canada.

出版信息

Opt Express. 2011 Aug 29;19(18):17575-84. doi: 10.1364/OE.19.017575.

DOI:10.1364/OE.19.017575
PMID:21935124
Abstract

In this paper, we propose and analyze novel ring resonator based bio-chemical sensors on silicon nanowire optical waveguide (SNOW) and show that the sensitivity of the sensors can be increased by an order of magnitude as compared to silicon-on-insulator based ring resonators while maintaining high index contrast and compact devices. The core of the waveguide is hollow and allows for introduction of biomaterial in the center of the mode, thereby increasing the sensitivity of detection. A sensitivity of 243 nm/refractive index unit (RIU) is achieved for a change in bulk refractive index. For surface attachment, the sensor is able to detect monolayer attachments as small as 1 Å on the surface of the silicon nanowires.

摘要

在本文中,我们提出并分析了基于硅纳米线光波导(SNOW)的新型环形谐振器生化传感器,并表明与基于绝缘体上硅的环形谐振器相比,该传感器的灵敏度可提高一个数量级,同时保持高折射率对比度和紧凑的器件尺寸。波导的核心是中空的,允许在模式中心引入生物材料,从而提高检测灵敏度。对于体折射率的变化,实现了243纳米/折射率单位(RIU)的灵敏度。对于表面附着,该传感器能够检测硅纳米线表面小至1埃的单层附着。

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引用本文的文献

1
Optical Ring Resonators: A Platform for Biological Sensing Applications.光学环形谐振器:用于生物传感应用的平台。
J Med Signals Sens. 2017 Jul-Sep;7(3):185-191.
2
Label-free detection with high-Q microcavities: a review of biosensing mechanisms for integrated devices.基于高品质因数微腔的无标记检测:集成器件生物传感机制综述
Nanophotonics. 2012 Dec;1(3-4):267-291. doi: 10.1515/nanoph-2012-0021. Epub 2012 Dec 6.