荧光 DNA 化学传感器：通过挥发性代谢物识别细菌种类。
Fluorescent DNA chemosensors: identification of bacterial species by their volatile metabolites.
机构信息
Department of Chemistry, Stanford University, Stanford, California 94305, USA.
出版信息
Chem Commun (Camb). 2011 Nov 7;47(41):11435-7. doi: 10.1039/c1cc14871k. Epub 2011 Sep 21.
Abstract
Polyfluorophores built on a DNA scaffold (ODFs) were synthesized and tested for fluorescence responses to the volatiles from M. tuberculosis, E. coli and P. putida in closed Petri dishes. Two sensors in a pattern-based response could distinguish the bacterial strains accurately, suggesting the use of ODFs in rapid identification of infectious agents.
摘要
基于 DNA 支架构建的多荧光团（ODFs）被合成，并在密闭的培养皿中测试了它们对结核分枝杆菌、大肠杆菌和恶臭假单胞菌挥发物的荧光响应。基于模式的两种传感器的响应可以准确地区分细菌株，这表明 ODFs 可用于快速鉴定感染因子。
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