School of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, People's Republic of China.
J Biomed Mater Res A. 2011 Dec 15;99(4):544-53. doi: 10.1002/jbm.a.33198. Epub 2011 Sep 20.
An in-situ nitriding method has been developed to modify the outer surface and the pore walls of both open and closed pores of porous NiTi shape memory alloys (SMAs) as part of their sintering process. XRD and XPS examinations revealed that the modified layer is mainly TiN. The biocompatibility of the in-situ nitrided sample has been characterized by its corrosion resistance, cell adherence, and implant surgery. The in-situ nitrided porous NiTi SMAs exhibit much better corrosion resistance, cell adherence, and bone tissue induced capability than the porous NiTi alloys without surface modification. Furthermore, the released Ni ion content in the blood of rabbit is reduced greatly by the in-situ nitriding. The excellent biocompatibility of in-situ nitrided sample is attributed to the formation of the TiN layer on all the pore walls including both open and closed pores.
一种原位氮化方法已被开发用于修改多孔 NiTi 形状记忆合金（SMA）的开放和封闭孔的外表面和孔壁，作为其烧结过程的一部分。XRD 和 XPS 检查表明，改性层主要是 TiN。通过耐腐蚀性、细胞黏附性和植入手术对原位氮化样品的生物相容性进行了表征。与未经过表面改性的多孔 NiTi 合金相比，原位氮化多孔 NiTi SMA 表现出更好的耐腐蚀性、细胞黏附性和骨组织诱导能力。此外，原位氮化大大降低了兔血中释放的 Ni 离子含量。原位氮化样品的优异生物相容性归因于 TiN 层在所有孔壁（包括开放孔和封闭孔）上的形成。
