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全血细胞中电介质参数与血液学参数的相关性分析

[The correlation analysis between dielectric parameters and haematological parameters in whole blood cell].

作者信息

Chen Xiaomin, Feng Mingjun, Wang Li, Chu Huimin, Chen Lin, Ma Qing

机构信息

Ningbo No. 1 Hospital, Ningbo 315010, China.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2011 Aug;28(4):694-7.

Abstract

We have measured the AC impedances of blood samples from 30 healthy adults with the Agilent 4294A impedance analyzer at frequency ranging 0.01-100MHz. At the same time, we measured the erythrocyte sedimentation rate (ESR), hematocrit (HCT), plasma fibrinogen (FIB), blood glucose (BG) and D-dimer. Then we analyzed the correlation between ESR and dielectric parameters of blood by linear correlation analysis, and used multiple regression analysis to reveal the influence of these hematological data on dielectric spectral characteristics of whole blood cell when these data were available. Statistical analysis showed that ESR had a linear correlation with the part of dielectric parameters in whole blood cell. The Multiple linear regression analysis indicated that HCT and BG had an influence on dielectric spectral characteristics of human whole blood cell, and HCT was the major factor in haematological parameters that influenced dielectric spectral characteristics of whole blood cell.

摘要

我们使用安捷伦4294A阻抗分析仪在0.01 - 100MHz频率范围内测量了30名健康成年人血液样本的交流阻抗。同时,我们测量了红细胞沉降率(ESR)、血细胞比容(HCT)、血浆纤维蛋白原(FIB)、血糖(BG)和D - 二聚体。然后通过线性相关分析分析了ESR与血液介电参数之间的相关性,并在这些数据可用时使用多元回归分析来揭示这些血液学数据对全血细胞介电谱特征的影响。统计分析表明,ESR与全血细胞中部分介电参数呈线性相关。多元线性回归分析表明,HCT和BG对人体全血细胞的介电谱特征有影响,并且HCT是影响全血细胞介电谱特征的血液学参数中的主要因素。

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