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用于治疗创伤的惠柳切植物药的抗菌评价。

Antimicrobial evaluation of Huilliche plant medicine used to treat wounds.

机构信息

Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.

出版信息

J Ethnopharmacol. 2011 Oct 31;138(1):219-27. doi: 10.1016/j.jep.2011.09.006. Epub 2011 Sep 12.

Abstract

ETHNOPHARMACOLOGICAL RELEVANCE

The traditional use of 40 plant species used for treatment of wounds and associated infections by the Huilliche people of Chile was evaluated against bacterial and fungal human pathogens, especially including wound pathogens.

MATERIALS AND METHODS

The extracts were tested against the fungi Penicillium expansum, Candida albicans and the bacteria Bacillus subtilis, Pseudomonas aeruginosa (four different strains), Staphylococcus aureus, Escherichia coli (four different strains), Streptococcus pneumoniae (four different strains with one being resistance to streptomycin).

RESULTS

Thirteen of the plant species have interesting antimicrobial activities, with that of Acaena argentea, Aristotelia chilensis, Blechnum chilense, Francoa appendiculta, Gevuina avellana and Laureliopsis philippiana being the most noteworthy.

CONCLUSIONS

The findings in the manuscript support the traditional use by the Huilliche people, and allow enhanced economical benefit and use by the locals. The results obtained on Acaena argentea, Aristotelia chilensis, Blechnum chilense, Francoa appendiculta, Gevuina avellana and Laureliopsis philippiana are of specific scientific interest, and further studies is needed in order to establish the active constituents of the species.

摘要

民族药理学相关性

智利怀伊勒切人传统上将 40 种植物用于治疗伤口和相关感染,本研究评估了这些植物提取物对人类细菌和真菌病原体的抑制作用,尤其是对伤口病原体的抑制作用。

材料与方法

测试了这些提取物对青霉属扩展青霉、白色念珠菌和枯草芽孢杆菌、铜绿假单胞菌(四种不同的菌株)、金黄色葡萄球菌、大肠杆菌(四种不同的菌株,其中一种对链霉素有耐药性)、肺炎链球菌(四种不同的菌株,其中一种对链霉素有耐药性)的抑制作用。

结果

13 种植物具有有趣的抗菌活性,其中,银叶补血草、智利酒果、智利鳞毛蕨、弗朗西亚appendiculta、智利巴旦杏和智利肖楠的活性最为显著。

结论

本研究结果支持了怀伊勒切人传统的使用方式,并为当地人提供了更多的经济效益和利用价值。银叶补血草、智利酒果、智利鳞毛蕨、弗朗西亚appendiculta、智利巴旦杏和智利肖楠的研究结果具有特殊的科学意义,需要进一步研究以确定这些物种的活性成分。

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