Epilepsy Center Kempenhaeghe, Heeze, The Netherlands.
Epilepsy Behav. 2011 Nov;22(3):518-22. doi: 10.1016/j.yebeh.2011.08.008. Epub 2011 Sep 21.
An association between language impairment and rolandic epilepsy is frequently reported. This impairment could be correlated with the amount of nocturnal epileptiform activity.
We retrospectively analyzed 26 children with rolandic epilepsy and/or rolandic spikes. All had undergone a 24-hour EEG and neuropsychological assessment within 2 weeks. Reading performance (reading words and sentences) and intelligence were measured.
There was a significant negative correlation between amount of nocturnal epileptiform activity and reading sentences R=-0.525 (P=0.008). There was a trend in this correlation for reading words R=-0.398 (P=0.054). We found a negative correlation between amount of nocturnal epileptiform activity and Verbal IQ (R=-0.51 P=0.08). No correlation was found between reading performance or Verbal IQ and amount of diurnal epileptiform activity.
Reading performance is impaired in children with rolandic epilepsy and is correlated with the amount of nocturnal epileptiform activity.
语言障碍与中央区癫痫之间存在关联，这一现象常被报道。这种障碍可能与夜间癫痫样活动的数量有关。
我们回顾性分析了 26 例患有中央区癫痫和/或中央区棘波的儿童。所有患者均在 2 周内接受了 24 小时脑电图和神经心理学评估。评估内容包括阅读表现（阅读单词和句子）和智力。
夜间癫痫样活动的数量与句子阅读呈显著负相关（R=-0.525，P=0.008）。这种相关性在单词阅读中呈趋势（R=-0.398，P=0.054）。我们发现夜间癫痫样活动的数量与言语智商呈负相关（R=-0.51，P=0.08）。而日间癫痫样活动的数量与阅读表现或言语智商均无相关性。
中央区癫痫患儿的阅读表现受损，且与夜间癫痫样活动的数量相关。
