Ikem Ifechukwude, Sumpio Bauer E
Department of Vascular Surgery, Yale University School of Medicine, New Haven, CT, USA.
Vascular. 2011 Dec;19(6):301-7. doi: 10.1258/vasc.2011.ra0049. Epub 2011 Sep 22.
Sub-Saharan Africa (SSA) is now facing a double burden of disease where patients are suffering from non-communicable diseases such as coronary heart disease, along with the burden of the current human immunodeficiency virus (HIV) epidemic. Due to this double burden, cardiovascular disease (CVD) prevention and treatment has been overlooked, allowing the rates to continue to rise unchecked. A series of searches were conducted using PubMed as the primary database. From these searches, journal articles were compiled that related to diabetes, obesity and smoking rates in SSA. Also, the prevalence of CVD in the USA was reviewed. Although the USA has higher rates of CVD now, the rates were on the decline compared with SSA. Due to 'Westernization' of SSA, the rates of CVD risk factors, such as diabetes, are expected to increase by 50%. Because of this, 80% of CVD deaths worldwide took place in developing countries like those in SSA. Although HIV/acquired immunodeficiency syndrome (AIDS) is the current epidemic in SSA, CVD disease poses a threat as the new epidemic because of the increasing rates of these CVD risk factors. Without combating this disease now, SSA is facing an epidemiological shift from AIDS to CVD being the leading cause of death.
撒哈拉以南非洲地区（SSA）目前正面临疾病的双重负担，患者既要承受诸如冠心病等非传染性疾病的折磨，又要应对当前人类免疫缺陷病毒（HIV）流行带来的负担。由于这种双重负担，心血管疾病（CVD）的预防和治疗被忽视了，导致其发病率持续 unchecked 上升。以PubMed作为主要数据库进行了一系列检索。通过这些检索，汇编了与SSA地区糖尿病、肥胖和吸烟率相关的期刊文章。此外，还回顾了美国心血管疾病的患病率。尽管美国目前心血管疾病的发病率较高，但与SSA相比，其发病率正在下降。由于SSA的“西方化”，糖尿病等心血管疾病风险因素的发病率预计将上升50%。因此，全球80%的心血管疾病死亡发生在像SSA地区这样的发展中国家。尽管HIV/获得性免疫缺陷综合征（AIDS）是SSA地区当前的流行病，但由于这些心血管疾病风险因素的发病率不断上升，心血管疾病正成为新的流行病并构成威胁。如果现在不抗击这种疾病，SSA地区正面临从AIDS到心血管疾病成为主要死因的流行病学转变。
“unchecked”在原文语境中似乎不太完整准确，推测可能是“uncheckedly”之类的，但按要求未做修改直接翻译了。
