Kennemer Gasthuis, Haarlem, The Netherlands.
Int Orthop. 2012 Oct;36(10):2033-9. doi: 10.1007/s00264-012-1613-7. Epub 2012 Jul 13.
Postoperative maintenance of high haemoglobin (Hb) levels and avoidance of homologous blood transfusions is important in total hip arthroplasty (THA). The introduction of a postoperative drainage autologous blood transfusion (ABT) system or no drainage following THA has resulted in reduction of homologous blood transfusion requirements compared with closed-suction drains. The purpose of this study was to examine which regimen is superior following THA.
A randomised controlled blinded prospective single-centre study was conducted in which 100 THA patients were randomly allocated to ABT or no drainage. The primary endpoint was the Hb level on the first postoperative day.
The postoperative collected drained blood loss was 274 (±154) ml in the ABT group, of which 129 (±119) ml was retransfused (0-400). There was no statistical difference in Hb levels on the first postoperative day (ABT vs no drainage: Hb 11.0 vs 10.9 g/dl), on consecutive days (day 3: Hb 10.7 vs 10.2, p = 0.08) or in total blood loss (1,506 vs 1,633 ml), homologous transfusions, pain scores, Harris Hip Score, SF-36 scores, length of hospital stay or adverse events.
The use of a postoperative autologous blood retransfusion drain did not result in significantly higher postoperative Hb levels or in less total blood loss or fewer homologous blood transfusions compared with no drain.
在全髋关节置换术(THA)中,维持术后高血红蛋白(Hb)水平和避免同种异体输血非常重要。与使用封闭式引流管相比,THA 术后引流自体输血(ABT)系统或不引流可减少同种异体输血的需求。本研究旨在探讨哪种方案在 THA 后更具优势。
本研究采用随机对照、盲法、前瞻性单中心研究,将 100 例 THA 患者随机分为 ABT 组或不引流组。主要终点是术后第 1 天的 Hb 水平。
ABT 组术后收集的失血量为 274(±154)ml,其中 129(±119)ml 被再输血(0-400)。术后第 1 天(ABT 组 vs 无引流组:Hb 11.0 vs 10.9 g/dl)、连续几天(第 3 天:Hb 10.7 vs 10.2,p=0.08)或总失血量(1506 vs 1633 ml)、同种异体输血、疼痛评分、Harris 髋关节评分、SF-36 评分、住院时间或不良事件方面,两组间 Hb 水平无统计学差异。
与不引流相比,术后使用自体血再输血引流管并未导致术后 Hb 水平显著升高,总失血量或同种异体输血减少。