Auger Dominique, Schalij Martin J, Bax Jeroen J, Delgado Victoria
Department of Cardiology, Leiden University Medical Centre, Leiden, Países Bajos.
Rev Esp Cardiol. 2011 Nov;64(11):1035-44. doi: 10.1016/j.recesp.2011.06.015. Epub 2011 Sep 22.
Cardiac resynchronization therapy improves clinical symptoms and prognosis of heart failure patients. However, it has been shown that up to 40% of patients do not respond to this therapy. Three main determinants of cardiac resynchronization therapy response have been identified: left ventricular dyssynchrony, left ventricular lead position, and extent and location of myocardial scar tissue. Two-dimensional echocardiography is the first imaging technique to evaluate patients who may be candidates for cardiac resynchronization therapy. However, a multimodality approach based on 3-dimensional imaging techniques may provide a more comprehensive evaluation of these patients by combining the assessment of the aforementioned pathophysiological determinants of cardiac resynchronization therapy response.
心脏再同步治疗可改善心力衰竭患者的临床症状和预后。然而，已有研究表明，高达40%的患者对这种治疗无反应。已确定心脏再同步治疗反应的三个主要决定因素：左心室不同步、左心室导线位置以及心肌瘢痕组织的范围和位置。二维超声心动图是评估可能适合心脏再同步治疗患者的首选成像技术。然而，基于三维成像技术的多模态方法，通过结合对上述心脏再同步治疗反应的病理生理决定因素的评估，可能会为这些患者提供更全面的评估。
