Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA.
Am J Med. 2011 Nov;124(11):1051-7. doi: 10.1016/j.amjmed.2011.05.034. Epub 2011 Sep 22.
Knowledge of cardiac filling pressures is critical in the diagnosis and management of patients with dyspnea or heart failure. Echocardiography and B-natriuretic peptide (BNP) testing are commonly used to estimate these pressures, but their incremental value beyond physical examination remains unknown.
Right and left heart filling pressures were prospectively estimated as "normal" or "abnormal" by staff cardiologists and cardiovascular trainees based upon physical examination findings alone, or examination coupled with echocardiographic and BNP data in patients referred for cardiac catheterization. Net reclassification improvement was calculated to determine whether echocardiographic/BNP data had incremental value in the determination of right and left heart pressures.
Two hundred fifteen observations were made by 9 examiners in 116 consecutive patients. Right and left heart pressures were accurately predicted from examination alone in 71% and 60% of observations, respectively. Examination-based accuracy was greater for staff cardiologists compared with trainees for right heart (82 vs 67%, P=.03) and left heart pressures (71% vs 55%, P=.03). Exposure to echocardiographic and BNP data did not enhance accuracy beyond bedside examination alone, both for left heart pressures (net reclassification improvement=-0.004; 95% confidence interval, -0.12-0.12) and right heart pressures (net reclassification improvement=0.02, 95% confidence interval, -0.09-0.13).
Cardiac filling pressures can be estimated from physical examination with modest accuracy, which is enhanced with experience. While echocardiographic and BNP data predict cardiac filling pressures, they may not provide information of incremental value beyond examination alone. Rigorous teaching and practice of cardiac examination skills should continue to be emphasized during medical training.
了解心脏充盈压对于呼吸困难或心力衰竭患者的诊断和治疗至关重要。超声心动图和 B 型利钠肽(BNP)检测常用于估计这些压力,但它们在体格检查之外的额外价值尚不清楚。
根据体格检查结果,由工作人员心脏病专家和心血管培训生前瞻性地单独估计右心和左心充盈压为“正常”或“异常”,或结合超声心动图和 BNP 数据在接受心脏导管检查的患者中进行检查。计算净重新分类改善,以确定超声心动图/BNP 数据在确定右心和左心压力方面是否具有额外价值。
9 名检查者在 116 例连续患者中进行了 215 次观察。单独通过检查可以准确预测 71%和 60%的观察中右心和左心压力。与培训生相比,工作人员心脏病专家在右心(82%比 67%,P=.03)和左心压力(71%比 55%,P=.03)方面的检查准确性更高。暴露于超声心动图和 BNP 数据并未增强单独床边检查以外的准确性,无论是左心压力(净重新分类改善=-0.004;95%置信区间,-0.12-0.12)还是右心压力(净重新分类改善=0.02,95%置信区间,-0.09-0.13)。
心脏充盈压可以通过体格检查以中等准确性来估计,经验可以提高准确性。虽然超声心动图和 BNP 数据可以预测心脏充盈压,但它们可能无法提供除单独检查以外的额外有价值的信息。在医学培训期间,应继续强调严格的心脏检查技能教学和实践。