Tucker James J, Yanagawa Franz, Grim Rod, Bell Theodore, Ahuja Vanita
York Hospital, York, Pennsylvania, USA.
Am Surg. 2011 Aug;77(8):1014-20. doi: 10.1177/000313481107700820.
Studies confirm that laparoscopic cholecystectomy (LC) is safe and efficacious for elderly patients. The purposes of this study were to evaluate if LC is underused in the elderly and if it is a safe option in that group. Open cholecystectomy (OC) and LC were compared in nonelderly (40 to 64 years) and elderly (65 years or older) matched patient groups identified with gallbladder disease using the American College of Surgeons National Surgical Quality Improvement Program database (2005 to 2008). Length of stay (LOS), 30-day complications, and mortality were evaluated as outcomes. Using multivariate logistic regression, independent predictors of OC were identified. After case-matching, each group had 11,926 patients. A χ(2) test showed that elderly (20.1 vs 15.0%, P < 0.001) were more likely to undergo OC. Elderly patients had significantly higher comorbidities and were operated on as emergent case (all P < 0.05). OC had longer LOS and mortality (all P < 0.05). Among 10 other variables in logistic regression, elderly had a higher likelihood of receiving OC (OR, 1.299; P < 0 0.001). Significant disparity exists between elderly and nonelderly patients in use of LC surgery. LC has a lower complication rate than OC; however, elderly undergo LC less often. Awareness needs to be raised for offering earlier operative intervention and the superior results of LC in the elderly.
研究证实,腹腔镜胆囊切除术(LC)对老年患者是安全有效的。本研究的目的是评估LC在老年患者中是否未得到充分应用,以及在该群体中它是否是一种安全的选择。使用美国外科医师学会国家外科质量改进计划数据库(2005年至2008年),对确诊患有胆囊疾病的非老年(40至64岁)和老年(65岁及以上)匹配患者组进行了开腹胆囊切除术(OC)和LC的比较。将住院时间(LOS)、30天并发症和死亡率作为结果进行评估。使用多因素逻辑回归分析确定OC的独立预测因素。病例匹配后,每组有11926例患者。χ²检验显示,老年患者(20.1%对15.0%,P<0.001)接受OC的可能性更高。老年患者的合并症明显更多,且多为急诊手术(所有P<0.05)。OC的住院时间更长,死亡率更高(所有P<0.05)。在逻辑回归分析的其他10个变量中,老年患者接受OC的可能性更高(OR,1.299;P<0.001)。老年患者和非老年患者在LC手术的使用上存在显著差异。LC的并发症发生率低于OC;然而,老年患者接受LC的频率较低。需要提高认识,以便为老年患者提供更早的手术干预以及LC的更好效果。