椎间盘退变的诊断工具与成像方法

Diagnostic tools and imaging methods in intervertebral disk degeneration.

作者信息

Majumdar Sharmila, Link Thomas M, Steinbach Lynne S, Hu Serena, Kurhanewicz John

机构信息

Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA.

出版信息

Orthop Clin North Am. 2011 Oct;42(4):501-11, viii. doi: 10.1016/j.ocl.2011.07.007.

DOI:10.1016/j.ocl.2011.07.007

PMID:21944587

Abstract

Low back pain has a negative impact on the economy and society. Intervertebral disk degeneration is linked to the occurrence of low back pain. MRI provides three-dimensional morphologic and biochemical information regarding the status of the disk. This article reviews new and evolving MRI disk-imaging techniques, including grading, relaxation-time measurements, diffusion, and contrast perfusion. In addition, high-resolution magic-angle spinning methods to correlate in vitro disk degeneration (with pain, etc) and in vivo spectroscopic results are discussed. With the potential for morphologic and biochemical characterization of the intervertebral disk, MRI shows promise as a tool to quantitatively assess disk health.

摘要

腰痛对经济和社会有负面影响。椎间盘退变与腰痛的发生有关。磁共振成像（MRI）可提供有关椎间盘状态的三维形态学和生物化学信息。本文综述了新出现和不断发展的MRI椎间盘成像技术，包括分级、弛豫时间测量、扩散和对比剂灌注。此外，还讨论了用于关联体外椎间盘退变（与疼痛等）和体内光谱学结果的高分辨率魔角旋转方法。由于具有对椎间盘进行形态学和生物化学特征描述的潜力，MRI有望成为定量评估椎间盘健康状况的工具。