Majumdar S
Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology, University of California, San Francisco, CA 94158, USA.
NMR Biomed. 2006 Nov;19(7):894-903. doi: 10.1002/nbm.1106.
Intervertebral disc disease is an emerging health concern and has a considerable negative effect on the economy and on society. MRI has a critical role in assessing the disc, but it is still a challenge to objectively correlate disc health and pain with images. In this paper, a review of MR disc imaging techniques including grading, relaxation time measurements, diffusion, and contrast perfusion is presented. In addition, high-resolution magic-angle spinning methods to correlate in vitro disc degeneration (with pain, etc) are discussed. With the potential for gaining morphological and biochemical information, MRI shows promise for quantitative assessment of disc health.
椎间盘疾病是一个新出现的健康问题，对经济和社会有相当大的负面影响。磁共振成像（MRI）在评估椎间盘方面起着关键作用，但将椎间盘健康状况和疼痛与图像进行客观关联仍是一项挑战。本文对包括分级、弛豫时间测量、扩散和对比剂灌注在内的磁共振椎间盘成像技术进行了综述。此外，还讨论了用于关联体外椎间盘退变（与疼痛等）的高分辨率魔角旋转方法。由于有获取形态学和生化信息的潜力，MRI在椎间盘健康状况的定量评估方面显示出前景。
