Department of Plant Systems Biology, VIB, Technologiepark, Gent, Belgium.
Curr Opin Plant Biol. 2011 Dec;14(6):674-82. doi: 10.1016/j.pbi.2011.08.006. Epub 2011 Sep 23.
Endocytosis in plants has an essential role not only for basic cellular functions but also for growth and development, hormonal signaling and communication with the environment including nutrient delivery, toxin avoidance, and pathogen defense. The major endocytic mechanism in plants depends on the coat protein clathrin. It starts by clathrin-coated vesicle formation at the plasma membrane, where specific cargoes are recognized and packaged for internalization. Recently, genetic, biochemical and advanced microscopy studies provided initial insights into mechanisms and roles of clathrin-mediated endocytosis in plants. Here we summarize the present state of knowledge and compare mechanisms of clathrin-mediated endocytosis in plants with animal and yeast paradigms as well as review plant-specific regulations and roles of this process.
植物内吞作用不仅对基本的细胞功能，而且对生长发育、激素信号转导以及与环境的交流（包括养分传递、毒素回避和病原体防御）都有重要作用。植物中主要的内吞作用机制依赖于网格蛋白包被蛋白。它始于质膜上网格蛋白包被小泡的形成，在此过程中，特定的货物被识别并包装以进行内化。最近，遗传学、生物化学和先进显微镜研究为植物中网格蛋白介导的内吞作用的机制和作用提供了初步的认识。在这里，我们总结了目前的知识状态，并比较了植物中网格蛋白介导的内吞作用与动物和酵母范例的机制，以及综述了该过程的植物特异性调节和作用。
