Aspetar, Research and Education Centre, Qatar Orthopaedic and Sports Medicine Hospital, PO Box 29222, Doha, Qatar.
Eur J Appl Physiol. 2012 Jun;112(6):1989-99. doi: 10.1007/s00421-011-2165-z. Epub 2011 Sep 23.
The aim of this study was to examine the influence of aerobic fitness and exercise intensity on the development of thermal and cardiovascular strain in uncompensable heat stress conditions. In three separate trials, eight aerobically trained and eight untrained subjects cycled to exhaustion at 60% (H60%) and 75% (H75%) of maximal oxygen uptake [Formula: see text] in 40°C conditions, and for 60 min at 60% [Formula: see text] in 18°C conditions (CON). Training status had no influence on time to exhaustion between trained (61 ± 10 and 31 ± 9 min) and untrained (58 ± 12 and 26 ± 10 min) subjects (H60% and H75%, respectively). Rectal temperature at exhaustion was also not significantly different between trained (39.8 ± 0.3, 39.3 ± 0.6 and 38.2 ± 0.3°C) and untrained (39.4 ± 0.5, 38.8 ± 0.5 and 38.2 ± 0.4°C) subjects, but was different between trials (H60%, H75% and CON, respectively; P < 0.01). However, because exercise was terminated on reaching the ethics approved rectal temperature limit in four trained subjects in the H60% trial and two in the H75% trial, it is speculated that increased rectal temperature may have further occurred in this cohort. Nonetheless, exhaustion occurred >96% of maximum heart rate in both cohorts and was accompanied by significant declines in stroke volume (15-26%), cardiac output (5-10%) and mean arterial pressure (9-13%) (P < 0.05). The increase in cardiovascular strain appears to represent the foremost factor precipitating fatigue during moderate and high intensity aerobic exercise in the heat in both trained and untrained subjects.
本研究旨在探讨有氧适能和运动强度对补偿性热应激条件下热和心血管应激发展的影响。在三项独立的试验中,8 名有氧训练者和 8 名非训练者在 40°C 条件下以 60%(H60%)和 75%(H75%)的最大摄氧量[Formula: see text]进行至力竭,以及在 18°C 条件下以 60%[Formula: see text]进行 60 分钟(CON)。训练状态对训练有素的(61±10 和 31±9 分钟)和未训练的(58±12 和 26±10 分钟)受试者之间的力竭时间没有影响(H60%和 H75%,分别)。直肠温度在力竭时在训练有素的(39.8±0.3、39.3±0.6 和 38.2±0.3°C)和未训练的(39.4±0.5、38.8±0.5 和 38.2±0.4°C)受试者之间也没有显著差异,但在试验之间有所不同(H60%、H75%和 CON,分别;P<0.01)。然而,由于在 H60%试验中有 4 名训练有素的受试者和在 H75%试验中有 2 名受试者达到了伦理批准的直肠温度限制,因此停止了运动,因此推测在这一组中直肠温度可能会进一步升高。尽管如此,在两个队列中,力竭发生在最大心率的>96%,同时伴随着每搏输出量(15-26%)、心输出量(5-10%)和平均动脉压(9-13%)的显著下降(P<0.05)。心血管应激的增加似乎代表了在热环境中进行中等和高强度有氧运动时,导致训练有素和未训练的受试者疲劳的首要因素。