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爱尔兰一家三级转诊诊所的功能性胃肠疾病谱。

The spectrum of functional gastrointestinal disorders in a tertiary referral clinic in Ireland.

机构信息

Department of Radiology, Alimentary Pharmabiotic Centre, Cork University Hospital, University College Cork, Wilton, Cork, Ireland.

出版信息

Ir J Med Sci. 2012 Mar;181(1):81-6. doi: 10.1007/s11845-011-0756-7. Epub 2011 Sep 24.

DOI:10.1007/s11845-011-0756-7
PMID:21947685
Abstract

BACKGROUND

The functional gastrointestinal disorders (FGIDs) are a heterogenous group of chronic conditions which cause troubling gastrointestinal symptoms. Though common and sometimes disabling, causing considerable social and economic burden, there is little recent literature on presentation or impact of FGIDs in Ireland.

AIM

To describe the characteristics of patients with FGIDs at a tertiary referral clinic in Ireland.

METHODS

A retrospective review of those attending a university hospital gastroenterology clinic with a special interest in FGIDs between January 1999 and July 2008 was performed. Data were mined from electronic outpatient records and clinic letters.

RESULTS

A total of 1,909 patients were included. Of these patients, 41.2% (787 of 1,909) received a diagnosis of FGID. FGID patients were predominantly (70.14%) female and the average age at first presentation was 38.3 years. Of these, 76% (598 of 787) were referred from general practice; 35.8% (282 of 787) received onward referrals to other specialties. Nine hundred FGIDs were diagnosed. The most common FGID was irritable bowel syndrome (633 of 900, 70.3%). In the FGID group, 13.1% of patients (103 of 787) had more than one FGID diagnosis. Females received a definitive diagnosis of FGID faster than males; mean diagnostic latency: 5.3 versus 6.4 months (p < 0.05). Sixty-six percent (523 of 787) of FGID patients had non-gastrointestinal co-morbidities, with 315 (60.2%) of these having more than one co-morbidity. The burden of non-GI co-morbidity was significantly higher in patients with overlapping functional syndromes than in patients with single FGID (p < 0.05).

CONCLUSIONS

In Ireland, FGIDs are common, represent a significant burden for the health-care system and deserve greater recognition and further research attention.

摘要

背景

功能性胃肠病(FGIDs)是一组异质性的慢性疾病,会引起胃肠道不适症状。尽管 FGIDs 很常见,有时甚至会致残,给社会和经济带来相当大的负担,但最近关于爱尔兰 FGIDs 的发病情况或影响的文献却很少。

目的

描述在爱尔兰一家三级转诊诊所就诊的 FGIDs 患者的特征。

方法

对 1999 年 1 月至 2008 年 7 月期间在一家大学医院胃肠病学诊所就诊、对 FGIDs 特别感兴趣的患者进行了回顾性研究。数据来自电子门诊记录和门诊信件。

结果

共纳入 1909 例患者。其中,41.2%(787/1909)患者被诊断为 FGID。FGID 患者主要为女性(70.14%),首次就诊的平均年龄为 38.3 岁。其中,76%(598/787)来自全科医生转诊;35.8%(282/787)接受了向其他专科的转科。共诊断出 900 种 FGIDs。最常见的 FGID 是肠易激综合征(633/900,70.3%)。在 FGID 组中,13.1%(103/787)的患者有不止一种 FGID 诊断。女性比男性更快获得 FGID 的明确诊断;平均诊断潜伏期:5.3 个月对 6.4 个月(p<0.05)。787 例 FGID 患者中有 66%(523/787)合并非胃肠道共病,其中 315 例(60.2%)有不止一种共病。重叠功能性综合征患者的非胃肠道共病负担明显高于单一 FGID 患者(p<0.05)。

结论

在爱尔兰,FGIDs 很常见,给医疗保健系统带来了很大的负担,应该得到更多的认识和进一步的研究关注。

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