Department of Cardiovascular Medicine, National Cardiovascular Center, Suita, Japan.
Angiology. 2012 Jul;63(5):380-5. doi: 10.1177/0003319711419359. Epub 2011 Sep 22.
Although patients with abdominal aortic aneurysm (AAA) often have other cardiovascular diseases (CVDs), the exact prevalence remains unclear. We aimed to determine the prevalence and predictors of coexistent silent atherosclerotic cardiovascular diseases (SACVDs) in patients with AAA without a history of CVD. Consecutive 157 patients with AAA (mean age, 73 years), without any previous history of CVD, were included. Silent myocardial ischemia (SMI), cerebrovascular disease (CeVD), peripheral artery disease (PAD), and thoracic aortic aneurysm (TAA) without symptoms coexisted in 29.3%, 25.5%, 15.9%, and 8.3%, respectively. The significant predictors of SMI were diabetes mellitus (P = .025) and male sex (P = .048). The significant predictor of silent CeVD was older age (P = .039). The borderline predictors of asymptomatic PAD and TAA were diabetes mellitus (P = .056) and AAA size (P = .053), respectively. Even with no previous symptomatic CVD, patients with AAA have high prevalence of coexistent SACVD.
尽管腹主动脉瘤(AAA)患者常伴有其他心血管疾病(CVDs),但其确切患病率仍不清楚。我们旨在确定无 CVD 病史的 AAA 患者并存无症状动脉粥样硬化性心血管疾病(SACVDs)的患病率和预测因素。连续纳入 157 例 AAA 患者(平均年龄 73 岁),均无 CVD 既往史。无症状性心肌缺血(SMI)、脑血管疾病(CeVD)、外周动脉疾病(PAD)和无症状性胸主动脉瘤(TAA)分别合并存在于 29.3%、25.5%、15.9%和 8.3%的患者中。SMI 的显著预测因素为糖尿病(P =.025)和男性(P =.048)。无症状性 CeVD 的显著预测因素为年龄较大(P =.039)。无症状性 PAD 和 TAA 的边缘预测因素分别为糖尿病(P =.056)和 AAA 大小(P =.053)。即使没有先前的有症状性 CVD,AAA 患者也存在高患病率并存无症状性 SACVD。