Division of Cancer Prevention and Control, College of Medicine, The Ohio State University, Suite 525, 1590 North High Street, Columbus, OH 43201, USA.
Cancer Epidemiol Biomarkers Prev. 2011 Nov;20(11):2354-61. doi: 10.1158/1055-9965.EPI-11-0562. Epub 2011 Sep 23.
Increasing knowledge about human papillomavirus (HPV) and HPV vaccine is a potentially important way to increase vaccination rates, yet few education interventions have addressed these topics. We report the results of an education intervention targeting three key groups who have contact with adolescent females.
We conducted HPV education intervention sessions during 2008 and 2009 in Guilford County, North Carolina. Parents (n = 376), healthcare staff (n = 118), and school staff (n = 456) attended the one-time sessions and completed self-administered surveys. Analyses used mixed regression models to examine the intervention's effects on participants' self-rated HPV knowledge, objectively assessed HPV and HPV vaccine knowledge, and beliefs about HPV vaccine.
Participants had relatively low levels of objectively assessed HPV and HPV vaccine knowledge prior to the intervention. The education intervention increased self-rated HPV knowledge among all three key groups (all P < 0.001), and objectively assessed knowledge about many aspects of HPV and HPV vaccine among healthcare and school staff members (all P < 0.05). Following the intervention, more than 90% of school staff members believed HPV and HPV vaccine education is worthwhile for school personnel and that middle schools are an appropriate venue for this education. Most parents (97%) and school staff members (85%) indicated they would be supportive of school-based vaccination clinics.
Our education intervention greatly increased HPV and HPV vaccine knowledge among groups influential to the HPV vaccination behaviors of adolescent females.
Education interventions represent a simple yet potentially effective strategy for increasing HPV vaccination and garnering stronger support for school-based vaccination clinics.
提高人们对人乳头瘤病毒（HPV）和 HPV 疫苗的认识，是提高疫苗接种率的一个潜在重要途径，但很少有教育干预措施涉及这些主题。我们报告了一项针对三个与少女接触的关键群体的教育干预措施的结果。
我们于 2008 年至 2009 年在北卡罗来纳州吉尔福德县进行了 HPV 教育干预活动。376 名家长、118 名医疗保健人员和 456 名学校工作人员参加了一次性课程，并完成了自我管理的调查。分析采用混合回归模型来检验干预对参与者自我评估的 HPV 知识、客观评估的 HPV 和 HPV 疫苗知识以及对 HPV 疫苗的信念的影响。
在干预前，参与者的客观评估 HPV 和 HPV 疫苗知识水平相对较低。教育干预提高了所有三个关键群体对 HPV 的自我评估知识（均 P <0.001），以及医疗保健和学校工作人员对 HPV 和 HPV 疫苗的许多方面的客观评估知识（均 P <0.05）。干预后，超过 90%的学校工作人员认为 HPV 和 HPV 疫苗教育对学校人员是有价值的，中学是进行这种教育的合适场所。大多数家长（97%）和学校工作人员（85%）表示，他们将支持学校为基础的疫苗接种诊所。
我们的教育干预大大提高了对少女 HPV 疫苗接种行为有影响的群体的 HPV 和 HPV 疫苗知识。
教育干预是一种简单但具有潜在效力的策略，可以提高 HPV 疫苗接种率，并为学校为基础的疫苗接种诊所争取更有力的支持。
