Scully P G, O'Shea B, Flanagan K P, Falkiner F R
St. James's Hospital, Dublin.
Ir J Med Sci. 1990 Apr;159(4):98-100. doi: 10.1007/BF02937439.
Direct Antibiotic Sensitivity Testing (DST) is a rapid means of diagnosing urinary tract infection (UTI) and obtaining antibiotic sensitivity patterns of the infecting organisms. In this study 227 urine samples from general practice were analysed using this technique with those obtained using the standard laboratory method. DST was shown to be 94.6% sensitive, and 80.7% specific. Escherichia coli was the commonest infecting organism. Augmentin was the most effective antibiotic tested, all organisms tested in vitro, being susceptible. Direct Sensitivity Testing is rapid, inexpensive, easy to perform, highly sensitive and specific. It should be considered by general practitioners as an alternative to the problems and delays involved in sending urine samples to the laboratory and in awaiting the results.
直接药敏试验（DST）是诊断尿路感染（UTI）并获取感染病原体抗生素敏感性模式的一种快速方法。在本研究中，使用该技术对来自全科医疗的227份尿液样本进行了分析，并与采用标准实验室方法获得的样本进行了比较。结果显示，直接药敏试验的敏感性为94.6%，特异性为80.7%。大肠杆菌是最常见的感染病原体。阿莫西林克拉维酸钾是测试中最有效的抗生素，所有体外测试的病原体均对其敏感。直接药敏试验快速、廉价、易于操作，且具有高度的敏感性和特异性。全科医生应考虑将其作为替代将尿液样本送检实验室并等待结果所涉及的问题和延误的一种选择。
