Chebotar G O, Chebotar S V
Tsitol Genet. 2011 Jul-Aug;45(4):67-78.
During the last decade plant growth and development have been investigated at the molecular level. Plant specific family GRAS-proteins plays one of the key roles in the molecular mechanisms of this process. In this report we highlight the importance of DELLA-proteins and show the model ofgibberellin signalling pathway in plants that starts from the binding of biologically active gibberellic acid with receptor and DELLA-protein. This complex stimulates ubiquitination and degradation of DELLA-proteins through the proteasome pathway. After degradation of DELLA-proteins the repression of plant growth stops that allows gibberellin response to occur. The role of DELLA-proteins as transcription factors is discussed.
在过去十年中，植物生长与发育已在分子水平上得到研究。植物特有的GRAS蛋白家族在这一过程的分子机制中发挥着关键作用之一。在本报告中，我们强调了DELLA蛋白的重要性，并展示了植物中赤霉素信号通路的模型，该通路始于生物活性赤霉素与受体和DELLA蛋白的结合。这种复合物通过蛋白酶体途径刺激DELLA蛋白的泛素化和降解。DELLA蛋白降解后，植物生长的抑制作用停止，从而使赤霉素响应得以发生。文中还讨论了DELLA蛋白作为转录因子的作用。
